Electrical Engineering And Systems Science

How to fast and accurately assess the severity level of COVID-19 is an essential problem, when millions of people are suffering from the pandemic around the world. Currently, the chest CT is regarded as a popular and informative imaging tool for COVID-19 diagnosis. However, we observe that there are two issues -- weak annotation and insufficient data that may obstruct automatic COVID-19 severity assessment with CT images. To address these challenges, we propose a novel three-component method, i.e., 1) a deep multiple instance learning component with instance-level attention to jointly classify the bag and also weigh the instances, 2) a bag-level data augmentation component to generate virtual bags by reorganizing high confidential instances, and 3) a self-supervised pretext component to aid the learning process. We have systematically evaluated our method on the CT images of 229 COVID-19 cases, including 50 severe and 179 non-severe cases. Our method could obtain an average accuracy of 95.8%, with 93.6% sensitivity and 96.4% specificity, which outperformed previous works.

Various methods have been proposed for authentication, including password or pattern drawing, which is clearly visible on personal electronic devices. However, these methods of authentication are more vulnerable, as passwords and cards can be forgotten, lost, or stolen. Therefore, a great curiosity has developed in individual authentication using biometric methods that are based on physical and behavioral features not possible to forget or be stolen. Authentication methods are used widely in portable devices since the lifetime of battery and time response are essential concerns in these devices. Due to the fact that these systems need to be fast and low power, designing efficient methods is still critical. We, in this paper, proposed a new low power and fast method for pupil segmentation based on approximate computing that under trading a minor level of accuracy, significant improvement in power assumption and time saving can be obtained and makes this algorithm suitable for hardware implementation. Furthermore, the experimental results of PSNR and SSIM show that the error rate in this method is negligible.

Fiber-reinforced ceramic-matrix composites are advanced materials resistant to high temperatures, with application to aerospace engineering. Their analysis depends on the detection of embedded fibers, with semi-supervised techniques usually employed to separate fibers within the fiber beds. Here we present an open computational pipeline to detect fibers in ex-situ X-ray computed tomography fiber beds. To separate the fibers in these samples, we tested four different architectures of fully convolutional neural networks. When comparing our neural network approach to a semi-supervised one, we obtained Dice and Matthews coefficients greater than 92.28±9.65% , reaching up to 98.42±0.03% , showing that the network results are close to the human-supervised ones in these fiber beds, in some cases separating fibers that human-curated algorithms could not find. The software we generated in this project is open source, released under a permissive license, and can be freely adapted and re-used in other domains. All data and instructions on how to download and use it are also available.

The dynamic range of our normal life can exceeds 120 dB, however, the smart-phone cameras and the conventional digital cameras can only capture a dynamic range of 90 dB, which sometimes leads to loss of details for the recorded image. Now, some professional hardware applications and image fusion algorithms have been devised to take wide dynamic range (WDR), but unfortunately existing devices cannot display WDR image. Tone mapping (TM) thus becomes an essential step for exhibiting WDR image on our ordinary screens, which convert the WDR image into low dynamic range (LDR) image. More and more researchers are focusing on this topic, and give their efforts to design an excellent tone mapping operator (TMO), showing detailed images as the same as the perception that human eyes could receive. Therefore, it is important for us to know the history, development, and trend of TM before proposing a practicable TMO. In this paper, we present a comprehensive study of the most well-known TMOs, which divides TMOs into traditional and machine learning-based category.

The speckle phenomenon remains a major hurdle for the analysis of SAR images. The development of speckle reduction methods closely follows methodological progress in the field of image restoration. The advent of deep neural networks has offered new ways to tackle this longstanding problem. Deep learning for speckle reduction is a very active research topic and already shows restoration performances that exceed that of the previous generations of methods based on the concepts of patches, sparsity, wavelet transform or total variation minimization. The objective of this paper is to give an overview of the most recent works and point the main research directions and current challenges of deep learning for SAR image restoration.

Since the advent of U-Net, fully convolutional deep neural networks and its many variants have completely changed the modern landscape of deep learning based medical image segmentation. However, the over dependence of these methods on pixel level classification and regression has been identified early on as a problem. Especially when trained on medical databases with sparse available annotation, these methods are prone to generate segmentation artifacts such as fragmented structures, topological inconsistencies and islands of pixel. These artefacts are especially problematic in medical imaging since segmentation is almost always a pre-processing step for some downstream evaluation. The range of possible downstream evaluations is rather big, for example surgical planning, visualization, shape analysis, prognosis, treatment planning etc. However, one common thread across all these downstream tasks is the demand of anatomical consistency. To ensure the segmentation result is anatomically consistent, approaches based on Markov/ Conditional Random Fields, Statistical Shape Models are becoming increasingly popular over the past 5 years. In this review paper, a broad overview of recent literature on bringing anatomical constraints for medical image segmentation is given, the shortcomings and opportunities of the proposed methods are thoroughly discussed and potential future work is elaborated. We review the most relevant papers published until the submission date. For quick access, important details such as the underlying method, datasets and performance are tabulated.

Convolutional neural networks, the state of the art for image segmentation, have been successfully applied to histology images by many computational researchers. However, the translatability of this technology to clinicians and biological researchers is limited due to the complex and undeveloped user interface of the code, as well as the extensive computer setup required. As an extension of our previous work (arXiv:1812.07509), we have developed a tool for segmentation of whole slide images (WSIs) with an easy to use graphical user interface. Our tool runs a state-of-the-art convolutional neural network for segmentation of WSIs in the cloud. Our plugin is built on the open source tool HistomicsTK by Kitware Inc. (Clifton Park, NY), which provides remote data management and viewing abilities for WSI datasets. The ability to access this tool over the internet will facilitate widespread use by computational non-experts. Users can easily upload slides to a server where our plugin is installed and perform human in the loop segmentation analysis remotely. This tool is open source, and has the ability to be adapted to segment of any pathological structure. For a proof of concept, we have trained it to segment glomeruli from renal tissue images, achieving an F-score > 0.97 on holdout tissue slides.

Early screening of patients is a critical issue in order to assess immediate and fast responses against the spread of COVID-19. The use of nasopharyngeal swabs has been considered the most viable approach; however, the result is not immediate or, in the case of fast exams, sufficiently accurate. Using Chest X-Ray (CXR) imaging for early screening potentially provides faster and more accurate response; however, diagnosing COVID from CXRs is hard and we should rely on deep learning support, whose decision process is, on the other hand, "black-boxed" and, for such reason, untrustworthy. We propose an explainable two-step diagnostic approach, where we first detect known pathologies (anomalies) in the lungs, on top of which we diagnose the illness. Our approach achieves promising performance in COVID detection, compatible with expert human radiologists. All of our experiments have been carried out bearing in mind that, especially for clinical applications, explainability plays a major role for building trust in machine learning algorithms.

We examine progress in the use of AI for detecting skin lesions, with particular emphasis on the erythema migrans rash of acute Lyme disease, and other lesions, such as those from conditions like herpes zoster (shingles), tinea corporis, erythema multiforme, cellulitis, insect bites, or tick bites. We discuss important challenges for these applications, in particular the problems of AI bias regarding the lack of skin images in dark skinned individuals, being able to accurately detect, delineate, and segment lesions or regions of interest compared to normal skin in images, and low shot learning (addressing classification with a paucity of training images). Solving these problems ranges from being highly desirable requirements -- e.g. for delineation, which may be useful to disambiguate between similar types of lesions, and perform improved diagnostics -- or required, as is the case for AI de-biasing, to allow for the deployment of fair AI techniques in the clinic for skin lesion analysis. For the problem of low shot learning in particular, we report skin analysis algorithms that gracefully degrade and still perform well at low shots, when compared to baseline algorithms: when using a little as 10 training exemplars per class, the baseline DL algorithm performance significantly degrades, with accuracy of 56.41%, close to chance, whereas the best performing low shot algorithm yields an accuracy of 85.26%.

Millions of cameras at edge are being deployed to power a variety of different deep learning applications. However, the frames captured by these cameras are not always pristine - they can be distorted due to lighting issues, sensor noise, compression etc. Such distortions not only deteriorate visual quality, they impact the accuracy of deep learning applications that process such video streams. In this work, we introduce AQuA, to protect application accuracy against such distorted frames by scoring the level of distortion in the frames. It takes into account the analytical quality of frames, not the visual quality, by learning a novel metric, classifier opinion score, and uses a lightweight, CNN-based, object-independent feature extractor. AQuA accurately scores distortion levels of frames and generalizes to multiple different deep learning applications. When used for filtering poor quality frames at edge, it reduces high-confidence errors for analytics applications by 17%. Through filtering, and due to its low overhead (14ms), AQuA can also reduce computation time and average bandwidth usage by 25%.