Rapid host switching in generalist Campylobacter strains erodes the signal for tracing human infections
Bethany L. Dearlove, Alison J. Cody, Ben Pascoe, Guillaume Méric, Daniel J. Wilson, Samuel K. Sheppard
Rapid host switching in generalist
Campylobacter strains erodes the signal for tracing human infections
Bethany L. Dearlove , Alison J. Cody , Ben Pascoe , Guillaume Méric , Daniel J. Wilson, *, Samuel K. Sheppard * Nuffield Department of Medicine, Experimental Medicine Division, University of Oxford, Oxford, UK Department of Zoology, University of Oxford, Oxford, UK College of Medicine, Institute of Life Science, Swansea University, Swansea, UK MRC CLIMB Consortium, Institute of Life Science, Swansea University, Swansea, UK Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK *These authors contributed equally to this work. § Corresponding author. Present address: Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom. Email: [email protected]
Running Title:
Rapid zoonosis in generalist
Campylobacter strains
Subject Category:
Evolutionary genetics
Abstract
Campylobacter jejuni and
Campylobacter coli are the biggest causes of bacterial gastroenteritis in the developed world, with human infections typically arising from zoonotic transmission associated with infected meat, especially poultry. Because this organism is not thought to survive well outside of the gut, host associated populations are genetically isolated to varying degrees. Therefore the likely origin of most
Campylobacter strains can be determined by host-associated variation in the genome. This is instructive for characterizing the source of human infection at the population level. However, some common strains appear to have broad host ranges, hindering source attribution. Whole genome sequencing has the potential to reveal fine-scale genetic structure associated with host specificity within each of these strains. We found that rates of zoonotic transmission among animal host species in ST-21, ST-45 and ST-828 clonal complexes were so high that the signal of host association is all but obliterated. We attributed 89% of clinical cases to a chicken source, 10% to cattle and 1% to pig. Our results reveal that common strains of
C. jejuni and
C. coli infectious to humans are adapted to a generalist lifestyle, permitting rapid transmission between different hosts. Furthermore, they show that the weak signal of host association within these complexes presents a challenge for pinpointing the source of clinical infections, underlining the view that whole genome sequencing, powerful though it is, cannot substitute for intensive sampling of suspected transmission reservoirs.
Keywords: attribution /
Campylobacter / multilocus sequence typing / transmission / zoonosis
Introduction
Campylobacter jejuni and
Campylobacter coli are zoonotic pathogens with broad host ranges, carried, apparently asymptomatically, as part of the gut microbiota of a range of wild and domesticated mammal and bird species. Common carriage in the gut of animals and poultry farmed for meat leads to numerous opportunities for contamination of food products, which may take place at various points from farm to fork (Neimann et al. , 2003). Human-to-human transmission is rare (Allos, 2001), hence
Campylobacter infection in humans tends to be sporadic, and seldom manifests as outbreaks except when a single point source results in direct transmission to many people, for example via contaminated drinking water (Palmer et al. , 1983; Pebody et al. , 1997; Engberg et al. , 1998; Clark et al. , 2003). The sources of human
Campylobacter infection have been well characterized at the population level. Genetic analysis, particularly using seven-locus multilocus sequence typing (MLST) data, has helped to attribute the sources of clinical infections by exploiting differences in the frequency of
Campylobacter strains that live in different animal and environmental reservoirs (McCarthy et al. , 2007). For example, isolates belonging to related sequence types (STs) from the ST-257 and ST-61 clonal complexes are strongly associated with chicken and ruminants respectively, while wild bird species are often colonised by phylogenetically divergent
Campylobacter lineages (Sheppard et al. , 2011; Griekspoor et al. , 2013). Independent MLST-based studies in England, Scotland and New Zealand found that over 95% of human infections are attributable to animals farmed for meat and poultry, with 56-76% of cases attributable to poultry in particular (Wilson et al. , 2008; Mullner et al. , 2009; Sheppard et al. , 2009).
However, at the individual isolate level, there is often considerable uncertainty in source attribution because some of the most common disease causing strains, notably those belonging to the ST-21, ST-45 and ST-828 clonal complexes, are regularly isolated from multiple animal species. This means that quantitative attribution to a single host reservoir is difficult using MLST data alone. The reason for the apparently broader host range of these lineages is not currently understood, and may reflect true host generalism (Gripp et al. , 2011; Sheppard et al. , 2014) or the existence of host restricted sublineages within these clonal complexes. The increasing availability of whole genome sequence data provides a potential solution to the challenge of attributing the origin of generalist strains in clinical samples, as a host-specific signal might be gleaned from the remaining 99.8% of the genome outside the seven loci sequenced by standard MLST. Genomics has been used to investigate direct transmission events in a range of bacterial species including
Staphylococcus aureus (Harris et al. , 2010; Price et al. , 2014),
Clostridium difficile (Eyre et al. , 2013) and
Mycobacterium tuberculosis (Walker et al. , 2013). This raises the prospect of enhancing understanding of
Campylobacter epidemiology, for example by identifying individual retailers or producers of
Campylobacter -contaminated food in cases of human infection, and detecting cryptic point source outbreaks (Cody et al. , 2013). Ultimately this information can help to inform targeted interventions and reduce the incidence of human campylobacteriosis (Sears et al. , 2011). In this study we investigated the utility of whole genome sequence data for improving the accuracy with which human cases can be attributed to particular animal reservoirs, by focusing on common strains that are difficult to attribute with MLST. Specifically, we sought to detect fine-scale host-specific genetic structuring within
C. jejuni
ST-21 and ST-45 complex and
C. coli
ST-828 complex isolates sampled from different animal species and to exploit that signal to improve human source attribution. We observed extraordinarily rapid rates of zoonotic transfer within these strains leading to little or no phylogenetic association with host species, limiting the ability of whole genome sequencing to improve source attribution, but revealing new insight into the transmission dynamics within these common
Campylobacter strains.
Materials and Methods
Sequences
The ST-21 and ST-45 (
C. jejuni ) and ST-828 (
C. coli ) clonal complexes were chosen as the focus of the study because they are among the most common lineages causing human disease, but are difficult to attribute to source populations using seven-locus MLST data (Wilson et al. , 2008; Sheppard et al. et al. , 2010; Cody et al. , 2013; Sheppard, Didelot, Jolley, et al. , 2013; Sheppard, Didelot, Meric, et al. , 2013; Sheppard et al. , 2014) (see Supplementary Table 1). Isolates belonging these complexes are predominantly associated with chicken and cattle, from where the majority of animal samples were obtained (13 chicken isolates from each of clonal complexes, and 7, 9 and 10 cattle isolates for the ST-21, ST-45 and ST-828 clonal complexes respectively). In addition, three ST-45 complex isolates were included from wild bird species, and six ST-828 complex isolates from pigs. Clinical disease isolates (328, 68 and 128 for the ST-21, ST-45 and ST-828 clonal complexes respectively) were obtained from a surveillance study of samples submitted to the microbiology laboratory of the John Radcliffe Hospital, Oxfordshire, United Kingdom (UK). After Illumina sequencing, the high coverage short reads were de novo assembled using Velvet (Zerbino and Birney, 2008), and the resulting contiguous sequences (‘contigs’) stored using BIGSdb (Jolley and Maiden, 2010). These contigs were then compared to the NCTC11168 reference sequence (Genbank accession number: AL111168) to identify genes using a BLAST search (Parkhill et al. , 2000; Gundogdu et al. , 2007). Orthologous genes were defined as homologous genes that had 70% or greater nucleotide identity, and less than 50% difference in alignment length. Genes for all isolates were then aligned using MUSCLE (Edgar, 2004), and concatenated into a single sequence per sample.
Accounting for ancestral recombination
There is good evidence that novel diversity in
Campylobacter is generated frequently by the continued movement of genes between lineages, more so even than by the evolution of new variants through mutation (Wilson et al. , 2009; Sheppard et al. , 2010). High levels of recombination lead to mosaic genomes with differing ancestral histories, and the full evolution of samples cannot be represented by a coalescent genealogy. During preliminary analyses using BEAST (Drummond et al. , 2012), a relaxed clock model and gamma site heterogeneity were used to try and account for the effect of recombination. However, these analyses diagnosed difficulties in the mixing of the MCMC algorithm underlying BEAST, with multiple runs of the same analysis frequently converging to different topologies. To overcome this, and to account for the effect that recombination has in skewing the branch lengths of the dominant phylogenetic tree (Schierup and Hein, 2000), homoplasious sites incompatible with the maximum likelihood tree were identified and removed (Pupko et al. , 2000; Guindon et al. , 2010). For the final dataset, only the biallelic sites compatible with the inferred phylogeny were included in the alignment, alongside all of the non-variable sites. The removal of homoplasies in this way resolved the mixing issues with BEAST. In addition, to improve computation time for later analyses, missing alleles were imputed using ClonalFrameML (Pupko et al. , 2000; Didelot and Wilson, 2015).
Phylogenetic analysis
The analysis was implemented in BEAST v1.7.5 (Drummond et al. , 2012), assuming a constant population size. All parameters were scaled in terms of the effective population size, , by fixing it to 1.0. The HKY85 model of nucleotide substitution (Hasegawa et al. , 1985) was used with an uncorrelated log-normal relaxed clock and gamma rate heterogeneity with four categories (Drummond et al. , 2006). A log-normal prior with a mean of 1.0 and standard deviation of 1.25 on the logarithmic-scale was assumed for the transition:tranversion ratio κ , and an exponential prior with a mean of 1.0 was utilized for the gamma shape parameter α . For the log-normal relaxed clock parameters, a uniform prior between 0.0 and 10.0 was assumed for the mean, and an exponential with mean 1.0 for the standard deviation. A uniform (Dirichlet) prior was used for the nucleotide frequencies. We used the phylogeographic model by Lemey et al. (Lemey et al. , 2009) to reconstruct zoonotic transmission and infer the source of the infection (host species) along the branches. This allows us to report the posterior probability of any node in the tree being a particular state (i.e. the most likely host of the ancestral lineage), and also to obtain relative rates of transition between states (i.e. switching between host species). Given that human to human transmission is rare (Allos, 2001), an ambiguity code was set up in the zoonotic model to allow the human isolates to have an ‘unknown’ source population. For each human isolate, the other host species in the analysis were given equal prior probability and thus most likely source of the human isolates could be inferred. A uniform prior from 0.0 to 100.0 was assumed for the host migration rate, a gamma prior with mean 1.0 and scale 1.0 for the relative rates of migration, and a uniform (Dirichlet) prior for the host population equilibrium frequencies. To calculate the number of discrete zoonotic transmissions across the branches, Markov jumping was performed using BEAST (Minin and Suchard, 2008a, 2008b; Talbi et al. , 2010). The MCMC was run for 500 million iterations, with samples taken every 10,000 iterations. For each ST, the analysis was repeated twice (three times for ST-21) with different initial values to check convergence and mixing, and these runs were combined for the final results. Unless otherwise stated, the posterior median was used for point estimates and the (2.5%, 97.5%) quantiles for credible intervals. The inferred ancestral host type for each branch in the phylogeny was taken to be the one with the highest posterior probability. Sample dates were not available for all isolates, so the analysis is given in coalescent time (denoted τ ) and calibrated to years using an independent estimate of the mutation rate in Campylobacter of 3.23 × 10 -5 substitutions per site per year from Wilson et al. (2009). Results
Fine-scale Phylogenetic Structure within Sequence Types
Within the ST-21, ST-45 and ST-828 complexes, isolates from different host species were often more closely related than those isolated from the same host species (Figure 1). If the strains harboured previously undetected sub-ST lineages that were strongly host associated, one would expect to see distinct clusters of the same coloured branches together. However, this was not the case, with branches of the same colour – representing the reconstructed reservoir population of that lineage – scattered throughout the tree in all STs. Furthermore, one could expect that isolates from mammalian hosts would be more closely related than those from avian species reflecting enhanced transfer potential between physiologically similar hosts. Again, this was not observed, with bird isolates in the ST-45 complex and pig isolates in ST-828 complex being closely related to both chicken and cattle isolates. This may suggest that the ability to colonise a specific host has either evolved several times throughout the tree, most plausibly through horizontal gene transfer given that mutation is rare, or that the isolates are adapted to infect all species of host in the sample. Much of the ancestral history of the lineages was inferred to have occurred within the chicken host population, shown by the dominance of yellow branches. The most recent common ancestor (MRCA) of all three clonal complexes was inferred to have colonized chicken, with posterior probabilities of 0.612, 0.498 and 0.500 for the ST-21, ST-45 and ST-828 complexes respectively.
Rates of Zoonotic Transmission in
Campylobacter
Under the host restricted hypothesis, isolates sampled from the same source reservoir will cluster into a single clade within the phylogeny. Since we sampled ST-21 complex isolates from two host species (chicken and cattle), there must have been exactly one zoonotic transfer in the tree under the restricted host hypothesis, or more under the generalist model. We sampled ST-45 and ST-828 complex isolates from three host species (chicken, cattle and wild birds in ST-45 or swine in ST-828), necessitating exactly two zoonotic transfer events in the tree under the restricted host hypothesis. In fact, the total number of migration events for all three clonal complexes was estimated to be much higher than these minimum values, with 588.9 (95% credibility interval: 109.8, 1325.9), 468.7 (105.7, 1264.5) and 117.7 (36.6, 456.3) cross-species transmission events for ST-21, ST-45 and ST-828 complexes respectively. In all three cases, the number of zoonotic transfers under the restricted host hypothesis was outside the range of the 95% credible intervals, demonstrating that isolates from these clonal complexes display host generalism and excluding the possibility of host restricted sub-lineages. The overall estimated migration rate was much more frequent in the
C. jejuni clonal complexes compared to the
C. coli (ST-828) complex. Using a mutation rate of 3.23 × 10 -5 substitutions per site per year for calibration (Wilson et al. , 2009), this corresponds to approximately one host jump every twelve years for ST-828 compared to one every 1.6 or 1.8 years in the ST-21 and ST-45 complexes. Although the credible intervals are wide, particularly for the C. jejuni sequence types, the finding of extraordinarily rapid rates of zoonotic transfer were robust to alternative prior beliefs. Thus, based upon the isolate collection in this study, the estimated rate of zoonosis is sufficiently rapid within ST-21 and ST-45 clonal complexes that there is no association between genetic structure and host species. This is consistent with a generalist lifestyle in which the isolates are equally adapted to transmission between versus within species.
Tracing the Source of Human Infection
In Figure 1, the human cases at the tips of the tree are represented with black circles, and the posterior probability of the sources for the human isolates are illustrated by the bar plots. The majority of clinical cases (462 out of 519 cases, or 89%) were attributed to a chicken source, with 53 cases (10%) attributed to cattle and 4 (1%) to pig (Figure 2). This is consistent with results found by MLST (Wilson et al. , 2008; Mullner et al. , 2009; Sheppard et al. , 2009), but the difficulty of attributing individual human cases to specific source species with high confidence, even using whole genomes, reflects the remarkable transmission rates of lineages among host species. Even when human isolates were most closely related to clades sampled only from chicken, there remained appreciable probabilities (in the range 30-40%) that the direct source of transmission was non-chicken. This degree of uncertainty is comparable to the 67% accuracy of source attribution that Wilson et al. (2008) achieve with MLST alone. Discussion
We investigated the source of
Campylobacter infection in humans using whole genome sequencing, focusing on STs that are frequently isolated from multiple host species and are therefore weakly host-associated on the basis of MLST (Wilson et al. , 2008; Sheppard et al. , 2009, 2014; Gripp et al. , 2011). We tested whether these STs were aggregations of strongly host-restricted sub-lineages, or whether they represented genuine generalists (Gripp et al. , 2011). We estimated rates of zoonotic transfer between
Campylobacter reservoir species, and attributed individual clinical cases to animal sources. Consistent with previous studies (Harris et al. , 1986; Wingstrand et al. , 2006; Wilson et al. , 2008; Mullner et al. , 2009; Sheppard et al. , 2009), we identified the chicken reservoir as accounting for the majority of human
Campylobacter infections, emphasizing the importance of measures aimed at controlling food-borne disease in agriculture and the food industry. We found that fine-scale population structure across the genome within the ST-21, ST-45 and ST-828 clonal complex isolates was not host-associated. This is consistent with the existence of genuine generalist strains, adapted to transmit between and live within multiple host species. There are clear advantages of a generalist lifestyle in agricultural animal species where multiple mammalian and avian species routinely live in close proximity, giving rise to frequent opportunity for zoonotic transmission. Some differences were observed in the relative rate of host switching between C. coli and
C. jejuni . Specifically, for the
C. coli
ST-828 complex isolates, there was evidence for slower rates of zoonotic transfer, compared to the
C. jejuni
ST-21 and ST-45 complex isolates. We estimated that there were 588 migration events across the tree in the ST-21 complex and 468 in the ST-45 complex, compared to only 117 in ST-828. In all cases we were able to reject the hypothesis of a unique host jump founding the population in each new species, with significantly more migration events than would be expected if isolates were host restricted (Table 2). This is evidenced by the scattering of isolates sampled from different sources throughout the phylogeny. The overall rates of migration between different host species provides information about the ecology of the generalist
Campylobacter strains. Within the ST-45 complex, there was very little difference in the relative rates of transmission between host species (Table 2). However, in ST-828 complex isolates, host switches were twice as frequent between cattle and swine compared with the rates of migration between these species and chicken. This disparity between mammal-mammal and mammal-bird transmission rates suggests that the efficacy of zoonotic transmission may be lower in the ST-828 complex compared to ST-21 or ST-45 complexes. Mammals and birds exhibit many physiological differences including a difference in core body temperature of about 38°C in cattle and pigs versus 42°C in chickens. Variation in rates of zoonosis may be explained by differences in the route of transmission between the mammalian species, either through opportunity – for example if cattle and pigs have more commonly shared the same physical environment, or through affinity – involving factors associated with the ability to colonize different species. Suggestively, the average genome size of ST-828 complex isolates is smaller than that of ST-21 and ST-45 complex isolates, potentially reflecting more limited phenotypic plasticity that would limit the ability to occupy multiple divergent niches. By comparing an approach using relatively few isolates characterized at many loci, by whole genome sequencing, with methods using hundreds or thousands of isolates characterized at few loci, such as MLST studies (Wilson et al. , 2008; Mullner et al. , 2009; Sheppard et al. , 2009), we investigated the added benefit of whole genome sequencing for investigating lineages with rapid host-switching within clonal complexes. There was little additional information regarding source of infection provided by the whole genome sequence in the majority of human cases. This suggests an inherent trade-off between the number of samples and the number of loci sequenced, and that the approximately thousand-fold increase in sequence information afforded by whole genomes over 7-locus MLST does not, on its own, eliminate the need for detailed sampling. While there is evidence of the potential for whole genome sequencing to provide greater resolution in detecting recent transmission of human Campylobacter infection from non-chicken sources, this study highlights the importance of intensive sampling of potential source populations and an understanding of host transmission ecology for effective source attribution.
Acknowledgements
This study was supported by the Oxford NIHR Biomedical Research Centre and the UKCRC Modernising Medical Microbiology Consortium, the latter funded under the UKCRC Translational Infection Research Initiative supported by the Medical Research Council, the Biotechnology and Biological Sciences Research Council and the National Institute for Health Research on behalf of the UK Department of Health (Grant G0800778) and the Wellcome Trust (Grant 087646/Z/08/Z). BLD is supported by a Medical Research Council Methodology Research Programme grant (grant number MR/J013862/1). AJC was supported by the United Kingdom Department for Environment, Food, and Rural Affairs and Food Standards Agency (grant number OZ0624). DJW is a Sir Henry Dale Fellow, jointly funded by the Wellcome Trust and the Royal Society (Grant 101237/Z/13/Z). SKS is funded by the Biotechnology and Biological Sciences Research Council (BBSRC), the Medical Research Council (MR/L015080/1) and the Wellcome Trust. This publication made use of the
Campylobacter
Multi Locus Sequence Typing website ( http://pubmlst.org/ campylobacter/ ) developed by Keith Jolley and sited at the University of Oxford (24). The development of this site has been funded by the Wellcome Trust. Supplementary information is available at The ISME Journal’s website.
Conflicts of Interest
The authors have no conflicts of interest to declare.
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Figure 1: Maximum clade credibility trees for the ST-21, ST-45 ST-828 complexes.
Tips are coloured by host from which the sample was isolated: chicken (yellow), cattle (red), pig (pink), wild bird (green) and human (black). Branches are coloured according to the ancestral source population inferred using the maximum posterior probability. Pie charts show the posterior probability for the root of the tree. For each human case, the posterior probability of source is shown as a stacked bar plot. Scale is given in units of coalescent time. Note that a change in host may have occurred at any point on the branch, not necessarily at the node, and it is also possible to have a number of host switches occurring along a branch. Figure 2: Probability of source for clinical cases for a) ST-21, b) ST-45 and c) ST-828.
The posterior probability of each human isolate (vertical bars) broken down by source population: chicken (yellow), cattle (red), pig (pink) and wild bird (green). The isolates have been reordered along the x-axis for visualisation purposes.
Table 1: Summary of sequence data for the three STs. ST-21 complex ST-45 complex ST-828 complex Genome alignment length: 1544595 1465323 1421603
Non-polymorphic sites 1447536 1386349 1272113 Polymorphic sites 97059 78929 149490
Biallelic sites: 90239 722233 136375
Compatible with ML tree 41895 34960 60692
Total sites used in analysis 1489431 1421309 1332805 Table 2: Parameter estimates for each ST. Parameter ST-21 complex ST-45 complex ST-828 complex Substitution rate (10 -3 /site / τ ) TMRCA
Coalescent time, τ Host switching rate / τ Number of migrations
Estimated host frequencies
Chicken 0.614 (0.388, 0.809) 0.498 (0.311, 0.685) 0.425 (0.136, 0.691) Cattle 0.386 (0.191, 0.612) 0.348 (0.185, 0.540) 0.282 (0.095, 0.562) Wild bird - 0.140 (0.0429, 0.313) - Pig - - 0.270 (0.103, 0.545)
Relative migration rates between host species
Chicken-Cattle 0.695 (0.023, 3.705) 0.820 (0.051, 3.779) 0.303 (0.010, 2.139) Chicken-Wild Bird - 0.592 (0.021, 3.282) - Chicken-Pig - - 0.581 (0.024, 3.129) Cattle-Wild Bird - 0.728 (0.031, 3.643) - Cattle-Pig - - 1.367 (0.192, 4.783) Using the mutation rate 3.23 × 10 -5 substitutions per site per year [21] for calibration with the median evolutionary rate from the BEAST analysis, one unit of coalescent time ( τ ) is equal to: 87.151 years in the ST-21 complex, 115.015 years in ST-45 complex, and 296.656 years in ST-828 complex. The median value was used for estimating all other parameters in years. Supplementary Table 1: Isolates included in the study.
All isolates are available from http://pubmlst.org/campylobacter/. *Sequence type was derived from the allelic profile of seven housekeeping genes by multilocus sequence typing (MLST). **Clonal complex is defined as including any ST that matches a previously defined central genotype (http://pubmlst.org/campylobacter/) at three or more loci. ***References refer to: 1. Sheppard SK, Didelot X, Jolley KA, Darling AE, Pascoe B, Meric G, Kelly DJ, Cody A, Colles FM, Strachan NJC, Ogden ID, Forbes K, French NP, Carter P, Miller WG, McCarthy ND, Owen R, Litrup E, Egholm M, Affourtit JP, Bentley SD, Parkhill J, Maiden MCJ, Falush D (2013) Progressive genome-wide introgression in agricultural
Campylobacter coli . Mol Ecol , :1051–64. 2. Sheppard SK, Didelot X, Meric G, Torralbo A, Jolley KA, Kelly DJ, Bentley SD, Maiden MCJ, Parkhill J, Falush D (2013) Genome-wide association study identifies vitamin B5 biosynthesis as a host specificity factor in Campylobacter. Proc Natl Acad Sci USA , :11923–11927. 3. Sheppard SK, Cheng L, Méric G, de Haan CPA, Llarena A-K, Marttinen P, Vidal A, Ridley A, Clifton-Hadley F, Connor TR, Strachan NJC, Forbes K, Colles FM, Jolley KA, Bentley SD, Maiden MCJ, Hänninen M-L, Parkhill J, Hanage WP, Corander J (2014) Cryptic ecology among host generalist Campylobacter jejuni in domestic animals.
Mol Ecol , :2442–51. 4. Lefébure T, Pavinski Bitar PD, Suzuki H, Stanhope MJ (2010) Evolutionary dynamics of complete Campylobacter pan-genomes and the bacterial species concept.
Genome Biol Evol , :646–55. 5. Cody AJ, McCarthy ND, Jansen van Rensburg M, Isinkaye T, Bentley SD, Parkhill J, Dingle KE, Bowler ICJW, Jolley KA, Maiden MCJ (2013) Real-time genomic epidemiological evaluation of human Campylobacter isolates by use of whole-genome multilocus sequence typing. J Clin Microbiol , :2526–34. ID Isolate source species aspA glnA gltA glyA pgm tkt uncA Sequence Type* Clonal Complex**
Reference***
1 NC_002163 human
Campylobacter jejuni
2 1 5 3 4 1 5 43 ST-21 complex
2 CampsClin262 human
Campylobacter jejuni
2 1 1 3 2 1 3 262 ST-21 complex
3 CampsClin266 human
Campylobacter jejuni
2 1 5 3 2 54 5 266 ST-21 complex
4 CampsClin883 human
Campylobacter jejuni
2 17 2 3 2 1 5 883 ST-21 complex
5 chicka21 chicken
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex
6 cow518 cattle
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex
7 CampsClin53 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex
8 cowa21 cattle
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex
9 chickc21 chicken
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex
10 chick104 chicken
Campylobacter jejuni
2 1 1 3 7 1 5 104 ST-21 complex
11 chick19 chicken
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex
12 chick50 chicken
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex
13 chick53 chicken
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex
14 chick262 chicken
Campylobacter jejuni
2 1 1 3 2 1 3 262 ST-21 complex
15 chick266 chicken
Campylobacter jejuni
2 1 5 3 2 54 5 266 ST-21 complex
16 chick1086 chicken
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex
17 chick1360 chicken
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex
18 cowb21 cattle
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex
19 cow104 cattle
Campylobacter jejuni
2 1 1 3 7 1 5 104 ST-21 complex
20 cow3201 cattle
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex
21 chickb21 chicken
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 3 22 chick883 chicken
Campylobacter jejuni
2 17 2 3 2 1 5 883 ST-21 complex 3 23 CampsClin21 human
Campylobacter jejuni
2 1 1 462 2 1 5 ST-21 complex 3 24 OxClina21 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 3 25 CjLMG9879 human
Campylobacter jejuni
2 1 1 5 2 1 5 47 ST-21 complex 4 26 Cj2008-1025 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 4 27 Cj2008-831 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 4 28 Cj110-21 cattle
Campylobacter jejuni
2 1 2 3 2 1 5 982 ST-21 complex 4
29 Cj87330 chicken
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 4 30 Cj1928 cattle
Campylobacter jejuni
2 1 1 3 140 3 5 806 ST-21 complex 4 31 OXC5333 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 32 OXC5335 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 33 OXC5344 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 34 OXC5349 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 35 OXC5350 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 36 OXC5364 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 37 OXC5372 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 38 OXC5378 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 39 OXC5393 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 40 OXC5397 human
Campylobacter jejuni
2 1 1 5 11 343 5 5242 ST-21 complex 5 41 OXC5474 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 42 OXC5476 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 43 OXC5664 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 44 OXC5671 human
Campylobacter jejuni
2 17 2 3 2 1 5 883 ST-21 complex 5 45 OXC5691 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 46 OXC5696 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 47 OXC5708 human
Campylobacter jejuni
2 1 42 3 148 1 5 861 ST-21 complex 5 48 OXC5710 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 49 OXC5713 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 50 OXC5720 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 51 OXC5495 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 52 OXC5617 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 53 OXC5618 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 54 OXC5625 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 55 OXC5628 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 56 OXC5639 human
Campylobacter jejuni
2 17 2 3 2 1 5 883 ST-21 complex 5 57 OXC5647 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 58 OXC5649 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5
59 OXC5651 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 60 OXC5652 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 61 OXC5835 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 62 OXC5498 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 63 OXC5840 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 64 OXC5841 human
Campylobacter jejuni
8 1 6 3 2 1 12 2135 ST-21 complex 5 65 OXC5843 human
Campylobacter jejuni
2 1 42 3 148 1 5 861 ST-21 complex 5 66 OXC5846 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 67 OXC5848 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 68 OXC5862 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 69 OXC5871 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 70 OXC5879 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 71 OXC5880 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 72 OXC5413 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 73 OXC5414 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 74 OXC5416 human
Campylobacter jejuni
2 1 12 3 2 1 23 3574 ST-21 complex 5 75 OXC5431 human
Campylobacter jejuni
2 1 1 3 492 1 5 5018 ST-21 complex 5 76 OXC5435 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 77 OXC5437 human
Campylobacter jejuni
2 17 2 3 2 1 5 883 ST-21 complex 5 78 OXC5438 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 79 OXC5444 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 80 OXC5445 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 81 OXC5451 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 82 OXC5462 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 83 OXC5463 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 84 OXC5465 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 85 OXC5470 human
Campylobacter jejuni
8 1 6 3 2 1 1 44 ST-21 complex 5 86 OXC5724 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 87 OXC5725 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 88 OXC5728 human
Campylobacter jejuni
2 1 5 3 2 61 5 2355 ST-21 complex 5
89 OXC5731 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 90 OXC5737 human
Campylobacter jejuni
2 1 5 3 2 54 5 266 ST-21 complex 5 91 OXC5739 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 92 OXC5754 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 93 OXC5757 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 94 OXC5766 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 95 OXC5767 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 96 OXC5771 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 97 OXC5772 human
Campylobacter jejuni
8 1 6 3 2 1 12 2135 ST-21 complex 5 98 OXC5774 human
Campylobacter jejuni
2 1 5 3 2 3 5 190 ST-21 complex 5 99 OXC5791 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 100 OXC5799 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 101 OXC5804 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 102 OXC5808 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 103 OXC5811 human
Campylobacter jejuni
8 1 6 3 2 1 12 2135 ST-21 complex 5 104 OXC5818 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 105 OXC5819 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 106 OXC5821 human
Campylobacter jejuni
8 1 6 3 2 1 12 2135 ST-21 complex 5 107 OXC5822 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 108 OXC5823 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 109 OXC5825 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 110 OXC5826 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 111 OXC5829 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 112 OXC5832 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 113 OXC5887 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 114 OXC5888 human
Campylobacter jejuni
8 1 6 3 2 1 12 2135 ST-21 complex 5 115 OXC5895 human
Campylobacter jejuni
8 1 6 3 2 1 12 2135 ST-21 complex 5 116 OXC5899 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 117 OXC5902 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 118 OXC5905 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5
119 OXC5906 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 120 OXC5909 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 121 OXC5918 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 122 OXC5937 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 123 OXC5924 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 124 OXC5925 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 125 OXC5926 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 126 OXC5929 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 127 OXC6548 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 128 OXC6552 human
Campylobacter jejuni
2 1 12 3 2 1 12 3769 ST-21 complex 5 129 OXC6558 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 130 OXC6562 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 131 OXC6563 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 132 OXC6564 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 133 OXC6565 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 134 OXC6571 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 135 OXC6573 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 136 OXC6251 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 137 OXC6257 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 138 OXC6266 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 139 OXC6270 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 140 OXC6275 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 141 OXC6277 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 142 OXC6282 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 143 OXC6285 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 144 OXC6286 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 145 OXC6289 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 146 OXC6292 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 147 OXC6300 human
Campylobacter jejuni
8 1 6 3 2 1 12 2135 ST-21 complex 5 148 OXC6301 human
Campylobacter jejuni
2 1 42 3 148 1 5 861 ST-21 complex 5
149 OXC6303 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 150 OXC6305 human
Campylobacter jejuni
2 1 42 3 148 1 5 861 ST-21 complex 5 151 OXC6310 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 152 OXC6317 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 153 OXC6324 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 154 OXC6325 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 155 OXC6326 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 156 OXC6329 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 157 OXC6331 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 158 OXC6334 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 159 OXC6335 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 160 OXC6340 human
Campylobacter jejuni
2 1 1 3 2 1 3 262 ST-21 complex 5 161 OXC6347 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 162 OXC6355 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 163 OXC6367 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 164 OXC6370 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 165 OXC6379 human
Campylobacter jejuni
2 1 5 462 2 1 5 5726 ST-21 complex 5 166 OXC6383 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 167 OXC6384 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 168 OXC6393 human
Campylobacter jejuni
2 1 12 462 2 1 5 5727 ST-21 complex 5 169 OXC6394 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 170 OXC6405 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 171 OXC6420 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 172 OXC6429 human
Campylobacter jejuni
2 1 1 3 492 1 5 5018 ST-21 complex 5 173 OXC6449 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 174 OXC6457 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 175 OXC6459 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 176 OXC6461 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 177 OXC6464 human
Campylobacter jejuni
2 1 1 3 492 1 5 5018 ST-21 complex 5 178 OXC6479 human
Campylobacter jejuni
2 17 2 3 2 1 5 883 ST-21 complex 5
179 OXC6483 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 180 OXC6489 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 181 OXC6493 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 182 OXC6496 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 183 OXC6500 human
Campylobacter jejuni
8 1 6 3 2 1 12 2135 ST-21 complex 5 184 OXC6502 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 185 OXC6505 human
Campylobacter jejuni
2 1 10 3 2 1 5 141 ST-21 complex 5 186 OXC6508 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 187 OXC6514 human
Campylobacter jejuni
2 84 12 3 11 1 5 3102 ST-21 complex 5 188 OXC6516 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 189 OXC6519 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 190 OXC6521 human
Campylobacter jejuni
2 1 1 5 2 1 5 47 ST-21 complex 5 191 OXC6524 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 192 OXC6527 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 193 OXC6530 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 194 OXC6531 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 195 OXC6538 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 196 OXC6539 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 197 OXC6543 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 198 OXC6255 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 199 OXC6590 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 200 OXC6596 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 201 OXC6598 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 202 OXC6600 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 203 OXC6602 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 204 OXC6603 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 205 OXC6604 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 206 OXC6613 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 207 OXC6615 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 208 OXC6616 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5
209 OXC6619 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 210 OXC6625 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 211 OXC6627 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 212 OXC6629 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 213 OXC6633 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 214 OXC6636 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 215 OXC6637 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 216 OXC6642 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 217 OXC6643 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 218 OXC6656 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 219 OXC6664 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 220 OXC6665 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 221 OXC6666 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 222 OXC6667 human
Campylobacter jejuni
8 1 6 3 2 1 1 44 ST-21 complex 5 223 OXC6671 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 224 OXC6672 human
Campylobacter jejuni
2 1 1 5 2 1 5 47 ST-21 complex 5 225 OXC6673 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 226 OXC6677 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 227 OXC6678 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 228 OXC6681 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 229 OXC6682 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 230 OXC6689 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 231 OXC6690 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 232 OXC6691 human
Campylobacter jejuni
2 1 5 3 2 3 5 190 ST-21 complex 5 233 OXC6702 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 234 OXC6703 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 235 OXC6706 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 236 OXC6711 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 237 OXC6712 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 238 OXC6713 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5
239 OXC6714 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 240 OXC6727 human
Campylobacter jejuni
2 2 52 3 2 100 5 5811 ST-21 complex 5 241 OXC6728 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 242 OXC6730 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 243 OXC6731 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 244 OXC6734 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 245 OXC6741 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 246 OXC6745 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 247 OXC6751 human
Campylobacter jejuni
8 1 6 3 2 1 12 2135 ST-21 complex 5 248 OXC6752 human
Campylobacter jejuni
8 1 6 3 2 1 12 2135 ST-21 complex 5 249 OXC6763 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 250 OXC6764 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 251 OXC6766 human
Campylobacter jejuni
2 1 1 3 2 1 3 262 ST-21 complex 5 252 OXC6779 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 253 OXC6781 human
Campylobacter jejuni
8 1 6 3 2 1 12 2135 ST-21 complex 5 254 OXC6786 human
Campylobacter jejuni
8 1 6 3 2 1 12 2135 ST-21 complex 5 255 OXC6789 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 256 OXC6791 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 257 OXC6798 human
Campylobacter jejuni
2 17 2 3 2 1 301 4526 ST-21 complex 5 258 OXC6804 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 259 OXC6812 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 260 OXC6815 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 261 OXC6820 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 262 OXC6823 human
Campylobacter jejuni
2 17 2 3 2 1 5 883 ST-21 complex 5 263 OXC6824 human
Campylobacter jejuni
2 1 1 3 2 1 3 262 ST-21 complex 5 264 OXC6833 human
Campylobacter jejuni
2 1 1 3 7 1 5 104 ST-21 complex 5 265 OXC6932 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 266 OXC6941 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 267 OXC6945 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 268 OXC6946 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5
269 OXC6948 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 270 OXC6949 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 271 OXC6953 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 272 OXC6956 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 273 OXC6959 human
Campylobacter jejuni
2 1 12 462 2 1 5 5727 ST-21 complex 5 274 OXC6961 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 275 OXC6964 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 276 OXC6979 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 277 OXC6981 human
Campylobacter jejuni
8 1 6 3 2 1 1 44 ST-21 complex 5 278 OXC6985 human
Campylobacter jejuni
2 17 12 462 2 1 5 6135 ST-21 complex 5 279 OXC6988 human
Campylobacter jejuni
2 1 5 462 2 1 5 5726 ST-21 complex 5 280 OXC6994 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 281 OXC6998 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 282 OXC7000 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 283 OXC7104 human
Campylobacter jejuni
2 1 5 10 2 1 6 6137 ST-21 complex 5 284 OXC7105 human
Campylobacter jejuni
2 1 5 10 2 1 6 6137 ST-21 complex 5 285 OXC7118 human
Campylobacter jejuni
2 1 5 3 2 54 5 266 ST-21 complex 5 286 OXC7132 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 287 OXC7134 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 288 OXC7136 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 289 OXC7137 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 290 OXC7140 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 291 OXC7141 human
Campylobacter jejuni
8 1 6 3 2 1 1 44 ST-21 complex 5 292 OXC7142 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 293 OXC7147 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 294 OXC7148 human
Campylobacter jejuni
2 1 79 3 2 1 5 822 ST-21 complex 5 295 OXC7150 human
Campylobacter jejuni
8 1 6 3 2 1 1 44 ST-21 complex 5 296 OXC7153 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 297 OXC7160 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 298 OXC7163 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5
299 OXC7168 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 300 OXC6836 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 301 OXC6845 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 302 OXC6850 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 303 OXC6852 human
Campylobacter jejuni
2 1 1 3 2 1 3 262 ST-21 complex 5 304 OXC6854 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 305 OXC6856 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 306 OXC6857 human
Campylobacter jejuni
2 1 12 88 2 1 5 520 ST-21 complex 5 307 OXC6860 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 308 OXC6861 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 309 OXC6862 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 310 OXC6865 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 311 OXC6867 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 312 OXC6868 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 313 OXC6872 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 314 OXC6876 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 315 OXC6879 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 316 OXC6886 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 317 OXC6892 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 318 OXC6900 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 319 OXC6909 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 320 OXC6922 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 321 OXC6924 human
Campylobacter jejuni
2 17 2 3 2 1 5 883 ST-21 complex 5 322 OXC6927 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 323 OXC7002 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 324 OXC7015 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 325 OXC7020 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 326 OXC7029 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 327 OXC7031 human
Campylobacter jejuni
2 17 2 3 2 1 5 883 ST-21 complex 5 328 OXC7035 human
Campylobacter jejuni
2 17 2 3 2 1 5 883 ST-21 complex 5
329 OXC7037 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 330 OXC7041 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 331 OXC7046 human
Campylobacter jejuni
8 1 6 3 2 1 12 2135 ST-21 complex 5 332 OXC7049 human
Campylobacter jejuni
2 1 5 3 2 54 5 266 ST-21 complex 5 333 OXC7058 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 334 OXC7065 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 335 OXC7068 human
Campylobacter jejuni
2 1 5 3 2 1 5 19 ST-21 complex 5 336 OXC7071 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 337 OXC7073 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 338 OXC7078 human
Campylobacter jejuni
2 1 5 3 2 25 5 1949 ST-21 complex 5 339 OXC7080 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 340 OXC7084 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 341 OXC7091 human
Campylobacter jejuni
2 1 1 3 2 1 3 262 ST-21 complex 5 342 OXC7089 human
Campylobacter jejuni
2 1 21 3 2 1 5 53 ST-21 complex 5 343 OXC7173 human
Campylobacter jejuni
8 1 6 3 2 1 1 44 ST-21 complex 5 344 OXC7187 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 345 OXC7188 human
Campylobacter jejuni
2 1 12 3 2 1 5 50 ST-21 complex 5 346 OXC7190 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 347 OXC7195 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 348 OXC6605 human
Campylobacter jejuni
2 1 1 3 2 1 5 21 ST-21 complex 5 349 CAMP45 chicken
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 1 350 CampsClin11 human
Campylobacter jejuni
48 7 10 4 1 7 1 11 ST-45 complex
351 chick2219 chicken
Campylobacter jejuni
10 7 10 4 1 7 1 2219 ST-45 complex
352 chick594 chicken
Campylobacter jejuni
4 7 10 4 42 51 1 583 ST-45 complex
353 cow334 cattle
Campylobacter jejuni
4 7 40 4 42 7 1 334 ST-45 complex
354 CampsClin230 human
Campylobacter jejuni
4 7 41 4 42 7 1 230 ST-45 complex
355 cowa45 cattle
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex
356 chick2213 chicken
Campylobacter jejuni
4 7 40 4 42 7 1 334 ST-45 complex
357 chickc45 chicken
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex
358 chick11 chicken
Campylobacter jejuni
48 7 10 4 1 7 1 11 ST-45 complex
359 chick1003 chicken
Campylobacter jejuni
8 7 4 4 125 7 1 1003 ST-45 complex
360 chick2048 chicken
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex
361 chick2223 chicken
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex
362 cowb45 cattle
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex
363 cowc45 cattle
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex
364 cowd45 cattle
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex
365 cow137 cattle
Campylobacter jejuni
4 7 10 4 42 7 1 137 ST-45 complex
366 cow583 cattle
Campylobacter jejuni
4 7 10 4 42 51 1 583 ST-45 complex
367 cow3207 cattle
Campylobacter jejuni
4 7 40 4 42 7 1 334 ST-45 complex 3 368 cow3214 cattle
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 3 369 chickb45 chicken
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 3 370 chickd45 chicken
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 3 371 chick230 chicken
Campylobacter jejuni
4 7 41 4 42 7 1 230 ST-45 complex 3 372 OxClina45 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 3 373 starling45 wild bird
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 3 374 goose137 wild bird
Campylobacter jejuni
4 7 10 4 42 7 1 137 ST-45 complex 3 375 duck45 wild bird
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 3 376 Cj55037 chicken
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 4 377 OXC5330 human
Campylobacter jejuni
8 7 4 4 125 7 1 1003 ST-45 complex 5 378 OXC5331 human
Campylobacter jejuni
4 7 10 4 42 7 1 137 ST-45 complex 5 379 OXC5332 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 380 OXC5343 human
Campylobacter jejuni
4 7 10 4 10 7 1 2109 ST-45 complex 5 381 OXC5850 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 382 OXC5420 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 383 OXC5434 human
Campylobacter jejuni
4 7 10 4 42 7 1 137 ST-45 complex 5 384 OXC5744 human
Campylobacter jejuni
4 7 10 4 42 7 1 137 ST-45 complex 5 385 OXC5816 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5
386 OXC5941 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 387 OXC6259 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 388 OXC6278 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 389 OXC6293 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 390 OXC6294 human
Campylobacter jejuni
4 7 10 4 42 51 1 583 ST-45 complex 5 391 OXC6313 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 392 OXC6314 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 393 OXC6321 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 394 OXC6330 human
Campylobacter jejuni
4 7 10 4 42 51 1 583 ST-45 complex 5 395 OXC6339 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 396 OXC6351 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 397 OXC6358 human
Campylobacter jejuni
2 7 10 4 1 7 1 233 ST-45 complex 5 398 OXC6365 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 399 OXC6419 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 400 OXC6437 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 401 OXC6448 human
Campylobacter jejuni
4 7 10 4 42 7 1 137 ST-45 complex 5 402 OXC6515 human
Campylobacter jejuni
4 7 73 4 1 7 1 845 ST-45 complex 5 403 OXC6536 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 404 OXC6592 human
Campylobacter jejuni
4 7 10 4 42 7 1 137 ST-45 complex 5 405 OXC6614 human
Campylobacter jejuni
2 7 10 4 1 7 1 233 ST-45 complex 5 406 OXC6624 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 407 OXC6797 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 408 OXC6803 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 409 OXC6819 human
Campylobacter jejuni
4 7 10 4 42 51 1 583 ST-45 complex 5 410 OXC6938 human
Campylobacter jejuni
4 7 10 4 10 7 1 2109 ST-45 complex 5 411 OXC6970 human
Campylobacter jejuni
4 7 10 4 42 51 1 583 ST-45 complex 5 412 OXC7103 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 413 OXC7113 human
Campylobacter jejuni
4 7 10 4 42 25 1 538 ST-45 complex 5 414 OXC7129 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 415 OXC7167 human
Campylobacter jejuni
4 7 10 4 1 532 1 6886 ST-45 complex 5
416 OXC7169 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 417 OXC6894 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 418 OXC6895 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 419 OXC6896 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 420 OXC6916 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 421 OXC7014 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 422 OXC7018 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 423 OXC7025 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 424 OXC7026 human
Campylobacter jejuni
10 7 10 4 1 7 1 2219 ST-45 complex 5 425 OXC7032 human
Campylobacter jejuni
4 7 10 4 42 51 1 583 ST-45 complex 5 426 OXC7061 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 427 OXC7067 human
Campylobacter jejuni
4 7 10 4 42 7 1 137 ST-45 complex 5 428 OXC7074 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 429 OXC7090 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 430 OXC7093 human
Campylobacter jejuni
48 7 10 4 1 7 1 11 ST-45 complex 5 431 OXC7099 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 432 OXC7170 human
Campylobacter jejuni
4 7 10 4 42 7 1 137 ST-45 complex 5 433 OXC7179 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 434 OXC7185 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 435 OXC7186 human
Campylobacter jejuni
4 7 10 4 1 7 1 45 ST-45 complex 5 436 171 human
Campylobacter coli
33 38 30 115 104 85 17 867 ST-828 complex 1 437 CAMP886 pig
Campylobacter coli
33 38 30 82 104 85 68 887 ST-828 complex 1 438 CAMP2588 chicken
Campylobacter coli
33 38 30 115 104 85 17 867 ST-828 complex 1 439 CAMP3129 human
Campylobacter coli
157 39 30 79 668 35 17 ST-828 complex 1 440 CAMP1090 chicken
Campylobacter coli
33 39 30 82 104 43 17 828 ST-828 complex
441 CAMP828 chicken
Campylobacter coli
33 39 30 82 104 43 17 828 ST-828 complex
442 cow3202 cattle
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex
443 Cc111-3 pig
Campylobacter coli
33 38 30 167 104 43 17 1467 ST-828 complex 4 444 CcZ163 chicken
Campylobacter coli
33 38 30 82 104 332 17 3336 ST-828 complex 4 445 Cc2553 chicken
Campylobacter coli
33 39 30 82 113 47 17 825 ST-828 complex 4
446 Cc2680 chicken
Campylobacter coli
33 39 103 82 104 324 41 3872 ST-828 complex 4 447 Cc2685 chicken
Campylobacter coli
33 39 30 82 211 85 17 1082 ST-828 complex 4 448 Cc2688 chicken
Campylobacter coli
33 39 30 82 104 43 41 1017 ST-828 complex 4 449 Cc2692 chicken
Campylobacter coli
33 39 30 79 113 47 17 860 ST-828 complex 4 450 Cc2698 chicken
Campylobacter coli
33 39 30 82 113 43 17 829 ST-828 complex 4 451 Cc84-2 pig
Campylobacter coli
33 38 30 78 104 35 17 1113 ST-828 complex 4 452 Cc80352 chicken
Campylobacter coli
33 39 30 82 104 43 41 1017 ST-828 complex 4 453 Cc86119 chicken
Campylobacter coli
33 39 30 82 113 47 17 825 ST-828 complex 4 454 Cc1091 cattle
Campylobacter coli
33 39 30 78 104 43 17 1068 ST-828 complex 4 455 Cc1098 cattle
Campylobacter coli
33 39 30 82 104 85 68 1104 ST-828 complex 4 456 Cc1148 cattle
Campylobacter coli
33 39 30 78 104 43 17 1068 ST-828 complex 4 457 Cc1417 cattle
Campylobacter coli
33 153 44 82 104 44 17 3221 ST-828 complex 4 458 Cc132-6 pig
Campylobacter coli
33 153 44 82 104 44 17 3221 ST-828 complex 4 459 Cc1891 cattle
Campylobacter coli
33 39 30 78 104 43 17 1068 ST-828 complex 4 460 Cc1909 cattle
Campylobacter coli
33 39 30 82 104 85 68 1104 ST-828 complex 4 461 Cc59-2 pig
Campylobacter coli
33 38 30 82 104 35 36 890 ST-828 complex 4 462 Cc1948 cattle
Campylobacter coli
33 39 30 82 104 85 68 1104 ST-828 complex 4 463 Cc1957 cattle
Campylobacter coli
33 153 30 82 104 85 68 2698 ST-828 complex 4 464 Cc1961 cattle
Campylobacter coli
33 39 30 82 104 85 68 1104 ST-828 complex 4 465 Cc202/04 human
Campylobacter coli
33 39 30 82 189 43 17 1585 ST-828 complex 4 466 Cc67-8 pig
Campylobacter coli
32 39 44 82 104 43 36 1061 ST-828 complex 4 467 CcLMG9854 human
Campylobacter coli
33 39 30 78 104 43 17 1068 ST-828 complex 4 468 CcLMG23336 human
Campylobacter coli
33 176 30 82 451 43 17 3868 ST-828 complex 4 469 CcLMG23341 human
Campylobacter coli
33 39 30 79 104 35 17 855 ST-828 complex 4 470 CcLMG23342 human
Campylobacter coli
33 39 30 79 104 35 17 855 ST-828 complex 4 471 CcLMG23344 human
Campylobacter coli
33 176 30 82 113 43 17 1586 ST-828 complex 4 472 CcLMG9853 human
Campylobacter coli
33 39 261 79 104 64 17 3869 ST-828 complex 4 473 CcH6 human
Campylobacter coli
33 176 30 79 113 43 17 3020 ST-828 complex 4 474 CcH8 human
Campylobacter coli
33 39 30 79 104 43 41 901 ST-828 complex 4 475 CCH9 human
Campylobacter coli
33 39 30 82 113 47 17 825 ST-828 complex 4
476 CcH56 human
Campylobacter coli
33 38 30 82 104 35 17 1096 ST-828 complex 4 477 CcZ156 chicken
Campylobacter coli
33 38 30 82 104 43 17 854 ST-828 complex 4 478 OXC5348 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 479 OXC5353 human
Campylobacter coli
33 39 30 79 530 43 17 5149 ST-828 complex 5 480 OXC5363 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 481 OXC5370 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 482 OXC5386 human
Campylobacter coli
33 39 30 82 113 47 17 825 ST-828 complex 5 483 OXC5677 human
Campylobacter coli
33 66 30 174 188 43 17 6132 ST-828 complex 5 484 OXC5685 human
Campylobacter coli
33 39 30 82 112 56 17 1578 ST-828 complex 5 485 OXC5688 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 486 OXC5705 human
Campylobacter coli
33 39 30 82 113 44 17 872 ST-828 complex 5 487 OXC5482 human
Campylobacter coli
33 39 65 79 104 85 17 2273 ST-828 complex 5 488 OXC5605 human
Campylobacter coli
33 39 30 79 113 43 17 832 ST-828 complex 5 489 OXC5629 human
Campylobacter coli
33 39 30 79 104 35 17 855 ST-828 complex 5 490 OXC5635 human
Campylobacter coli
124 39 30 79 104 47 17 1541 ST-828 complex 5 491 OXC5837 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 492 OXC5842 human
Campylobacter coli
33 39 66 82 104 44 174 2178 ST-828 complex 5 493 OXC5849 human
Campylobacter coli
33 39 30 79 104 47 17 830 ST-828 complex 5 494 OXC5853 human
Campylobacter coli
33 39 30 79 104 47 17 830 ST-828 complex 5 495 OXC5855 human
Campylobacter coli
33 39 30 82 113 47 17 825 ST-828 complex 5 496 OXC5856 human
Campylobacter coli
33 39 30 79 104 47 17 830 ST-828 complex 5 497 OXC5864 human
Campylobacter coli
33 39 30 82 189 47 17 1191 ST-828 complex 5 498 OXC5473 human
Campylobacter coli
33 39 30 82 23 43 17 6131 ST-828 complex 5 499 OXC5723 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 500 OXC5742 human
Campylobacter coli
33 39 30 82 113 44 17 872 ST-828 complex 5 501 OXC5763 human
Campylobacter coli
33 39 30 82 113 47 17 825 ST-828 complex 5 502 OXC5773 human
Campylobacter coli
33 39 30 82 104 43 17 828 ST-828 complex 5 503 OXC5796 human
Campylobacter coli
33 39 30 82 113 44 17 872 ST-828 complex 5 504 OXC5810 human
Campylobacter coli
33 39 30 82 189 44 17 5165 ST-828 complex 5 505 OXC5827 human
Campylobacter coli
33 39 30 79 113 47 17 860 ST-828 complex 5
506 OXC5831 human
Campylobacter coli
33 39 30 82 189 47 17 1191 ST-828 complex 5 507 OXC5922 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 508 OXC5923 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 509 OXC6559 human
Campylobacter coli
33 38 30 466 104 43 17 5757 ST-828 complex 5 510 OXC6568 human
Campylobacter coli
33 39 30 82 113 44 17 872 ST-828 complex 5 511 OXC6576 human
Campylobacter coli
33 39 30 79 104 35 17 855 ST-828 complex 5 512 OXC6577 human
Campylobacter coli
33 39 30 82 113 44 17 872 ST-828 complex 5 513 OXC6253 human
Campylobacter coli
33 39 30 82 113 43 17 829 ST-828 complex 5 514 OXC6258 human
Campylobacter coli
33 39 30 79 113 47 17 860 ST-828 complex 5 515 OXC6263 human
Campylobacter coli
33 39 30 79 104 47 17 830 ST-828 complex 5 516 OXC6267 human
Campylobacter coli
33 39 30 79 247 43 17 5642 ST-828 complex 5 517 OXC6276 human
Campylobacter coli
33 39 65 82 596 47 17 5733 ST-828 complex 5 518 OXC6296 human
Campylobacter coli
87 39 30 79 243 43 17 5737 ST-828 complex 5 519 OXC6297 human
Campylobacter coli
33 39 30 82 113 47 17 825 ST-828 complex 5 520 OXC6308 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 521 OXC6309 human
Campylobacter coli
33 110 30 115 104 43 17 5734 ST-828 complex 5 522 OXC6312 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 523 OXC6337 human
Campylobacter coli
33 39 65 140 104 43 17 1600 ST-828 complex 5 524 OXC6338 human
Campylobacter coli
33 39 30 79 104 206 17 1628 ST-828 complex 5 525 OXC6343 human
Campylobacter coli
33 39 30 82 104 47 36 962 ST-828 complex 5 526 OXC6371 human
Campylobacter coli
33 110 30 115 104 43 17 5734 ST-828 complex 5 527 OXC6372 human
Campylobacter coli
33 39 30 139 113 47 17 4425 ST-828 complex 5 528 OXC6376 human
Campylobacter coli
33 110 30 115 104 43 17 5734 ST-828 complex 5 529 OXC6378 human
Campylobacter coli
33 39 30 139 113 47 17 4425 ST-828 complex 5 530 OXC6380 human
Campylobacter coli
33 39 30 82 113 47 353 5735 ST-828 complex 5 531 OXC6385 human
Campylobacter coli
33 39 30 79 104 206 17 1628 ST-828 complex 5 532 OXC6386 human
Campylobacter coli
33 39 30 82 113 43 17 829 ST-828 complex 5 533 OXC6400 human
Campylobacter coli
33 39 30 82 113 47 17 825 ST-828 complex 5 534 OXC6416 human
Campylobacter coli
33 39 30 82 104 44 17 1145 ST-828 complex 5 535 OXC6424 human
Campylobacter coli
33 39 30 82 113 47 17 825 ST-828 complex 5
536 OXC6426 human
Campylobacter coli
32 66 66 82 104 43 17 2464 ST-828 complex 5 537 OXC6428 human
Campylobacter coli
33 39 30 79 113 43 17 832 ST-828 complex 5 538 OXC6447 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 539 OXC6460 human
Campylobacter coli
124 39 30 79 104 47 17 1541 ST-828 complex 5 540 OXC6471 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 541 OXC6472 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 542 OXC6474 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 543 OXC6476 human
Campylobacter coli
33 39 30 79 113 47 17 860 ST-828 complex 5 544 OXC6504 human
Campylobacter coli
33 39 30 79 113 43 17 832 ST-828 complex 5 545 OXC6513 human
Campylobacter coli
33 39 30 82 104 43 17 828 ST-828 complex 5 546 OXC6523 human
Campylobacter coli
33 66 30 82 113 206 17 5659 ST-828 complex 5 547 OXC6537 human
Campylobacter coli
124 39 30 79 104 47 17 1541 ST-828 complex 5 548 OXC6597 human
Campylobacter coli
33 39 30 79 104 35 17 855 ST-828 complex 5 549 OXC6601 human
Campylobacter coli
33 39 30 79 104 85 17 1614 ST-828 complex 5 550 OXC6630 human
Campylobacter coli
33 39 30 82 104 44 17 1145 ST-828 complex 5 551 OXC6651 human
Campylobacter coli
33 39 66 174 104 43 41 1181 ST-828 complex 5 552 OXC6684 human
Campylobacter coli
33 39 30 82 104 47 36 962 ST-828 complex 5 553 OXC6685 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 554 OXC6705 human
Campylobacter coli
33 39 65 79 104 35 17 1957 ST-828 complex 5 555 OXC6710 human
Campylobacter coli
2 39 30 82 113 47 17 5810 ST-828 complex 5 556 OXC6725 human
Campylobacter coli
33 38 30 82 104 35 17 1096 ST-828 complex 5 557 OXC6735 human
Campylobacter coli
33 39 30 82 104 44 17 1145 ST-828 complex 5 558 OXC6738 human
Campylobacter coli
33 39 65 79 104 85 17 2273 ST-828 complex 5 559 OXC6744 human
Campylobacter coli
53 39 30 82 603 43 17 5813 ST-828 complex 5 560 OXC6761 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 561 OXC6765
Campylobacter coli
33 39 30 79 113 43 17 832 ST-828 complex 5 562 OXC6785 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 563 OXC6810 human
Campylobacter coli
33 39 30 82 113 47 17 825 ST-828 complex 5 564 OXC6817 human
Campylobacter coli
33 39 30 82 104 47 36 962 ST-828 complex 5 565 OXC6825 human
Campylobacter coli
33 39 30 79 113 43 41 2183 ST-828 complex 5
566 OXC6933 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 567 OXC6937 human
Campylobacter coli
33 176 30 82 104 43 17 3753 ST-828 complex 5 568 OXC6962 human
Campylobacter coli
33 39 65 79 104 85 17 2273 ST-828 complex 5 569 OXC6984 human
Campylobacter coli
33 39 30 82 104 47 17 1055 ST-828 complex 5 570 OXC6987 human
Campylobacter coli
33 39 30 82 113 47 17 825 ST-828 complex 5 571 OXC6996 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 572 OXC7102 human
Campylobacter coli
33 39 30 82 189 47 17 1191 ST-828 complex 5 573 OXC7110 human
Campylobacter coli
33 39 30 82 189 47 17 1191 ST-828 complex 5 574 OXC7124 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 575 OXC7130 human
Campylobacter coli
33 39 30 79 113 43 41 2183 ST-828 complex 5 576 OXC7131 human
Campylobacter coli
33 39 30 82 104 43 17 828 ST-828 complex 5 577 OXC7154 human
Campylobacter coli
33 39 30 82 104 43 17 828 ST-828 complex 5 578 OXC7164 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 579 OXC6847 human
Campylobacter coli
33 39 30 82 113 43 17 829 ST-828 complex 5 580 OXC6864 human
Campylobacter coli
33 39 30 82 113 43 17 829 ST-828 complex 5 581 OXC6873 human
Campylobacter coli
33 39 30 81 561 47 17 5349 ST-828 complex 5 582 OXC6901 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 583 OXC6920 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 584 OXC7027 human
Campylobacter coli
33 38 30 82 118 43 17 1016 ST-828 complex 5 585 OXC7051 human
Campylobacter coli
33 38 30 82 118 43 17 1016 ST-828 complex 5 586 OXC7054 human
Campylobacter coli
33 39 30 82 113 47 17 825 ST-828 complex 5 587 OXC7070 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 588 OXC7082 human
Campylobacter coli
33 39 30 82 113 47 17 825 ST-828 complex 5 589 OXC7083 human
Campylobacter coli
33 39 30 79 104 35 17 855 ST-828 complex 5 590 OXC7097 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 591 OXC7177 human
Campylobacter coli
33 39 30 139 113 47 17 4425 ST-828 complex 5 592 OXC7199 human
Campylobacter coli
33 39 30 82 104 56 17 827 ST-828 complex 5 593 OXC7200 human
Campylobacter coli
33 39 30 82 113 43 17 829 ST-828 complex 533 39 30 82 113 43 17 829 ST-828 complex 5