A brief introduction to the technique! Why will PDEK surgery become the future choice for corneal transplantation?

In today's ophthalmic surgery, Pre Descemet's Endothelial Keratoplasty (PDEK) surgery is gradually becoming a bright option for corneal transplantation. The emergence of this technology not only revolutionized the traditional corneal transplant method, but also brought new hope to many patients with damaged corneas. So, what are the unique advantages of PDEK compared with traditional corneal transplantation?

PDEK technology corrects vision loss caused by endothelial dysfunction by transplanting Descemet's membrane and endothelial cells in the inner layer of the cornea.

Definition of PDEK Technology

While conventional corneal transplants mainly involve transplantation of the entire cornea or its layers, PDEK surgery is different and involves the precise transplantation of the endothelial layer. Since 2013, this technology has been widely used to treat various vision problems caused by endothelial dysfunction.

History of surgery

Speaking of the history of PDEK, it is worth mentioning that on September 4, 2013, Professor Amar Agarwal of India and Professor Haminder Dua of the United Kingdom successfully performed this operation for the first time. It marks a major breakthrough in corneal transplantation technology. As research on corneas from young donors continues, the medical community has a deeper understanding of the surgery's data and effects.

Indications and recipient age range

PDEK surgery is mainly suitable for a variety of corneal pathological conditions, such as corneal edema caused by pseudocataract, congenital endothelial decline, etc. In addition, the recipient age range of this technology is not demanding, and theoretically, donated corneas of any age can be accepted, which greatly increases the flexibility of PDEK surgery.

Surgical Procedure

During the procedure, doctors extract the inner layer of the cornea, called PDL, from the donor's cornea and separate the layers with high precision. Once in the patient's eye, multiple steps are usually required to ensure the success of the transplant.

After surgery is complete, the patient's medication and monitoring plan, including topical steroids and antibiotics, will help increase the success of the surgery and recovery.

Advantages and future prospects of PDEK

Compared with traditional full corneal transplantation, PDEK has many advantages. For example, since the thickness of PDEK transplantation is relatively thin, the probability of rejection reaction in patients is significantly reduced. Additionally, the procedure can restore vision more quickly and minimize surgery-related complications.

Clinical Outcomes of Surgery

According to clinical studies, patients who undergo PDEK surgery generally experience better visual recovery for a period of time after the operation. Over time, the success rate of the surgery has continued to improve through the use of corneas from younger donors.

Challenges and future research directions

Although PDEK surgery has many advantages over traditional corneal transplantation, the medical community still faces some challenges in terms of technical mastery and postoperative care. Future research will focus on further determining the best way to utilize corneas from donors of different ages and understanding how to maximize their regenerative capacity.

When considering the future of corneal transplantation, PDEK surgery has undoubtedly shown its unparalleled potential. Such progress makes us reflect: As corneal transplant technology continues to advance, will there be more revolutionary ways to improve vision in the future?

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