Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by persistent respiratory symptoms and air flow limitation. According to the 2024 GOLD definition, COPD is a heterogeneous lung disease characterized by chronic respiratory symptoms such as shortness of breath, cough, and sputum production or acute exacerbations, which are caused by abnormalities in the airways or alveoli. This results in persistent and often progressive airflow obstruction. Although COPD is not curable, it is a preventable and treatable disease.
The main symptoms of COPD include shortness of breath and cough, which may become worse over time. Shortness of breath is a core symptom of COPD and most patients experience difficulty carrying out daily activities, even with the slightest movement such as walking or getting dressed.
During the progression of COPD, patients often experience anxiety and powerlessness, which not only affects their quality of life but also their mental health.
Chronic bronchitis and emphysema are the two main types of COPD. Although they both belong to COPD, their pathological mechanisms and symptoms are different. Chronic bronchitis is characterized by a persistent, sputum-producing cough that occurs at least three months a year for two years, while emphysema is the enlargement of the air spaces due to the destruction of the walls of the alveoli, causing permanent damage to lung tissue.
While both emphysema and chronic bronchitis may lead to a diagnosis of COPD, some patients may have both conditions.
Smoking is the most common risk factor for COPD. Other risk factors include indoor and outdoor air pollution, exposure to occupational irritants, and genetic factors such as alpha-1 antitrypsin deficiency. Charcoal fires and biomass fuel use are also common sources of residential air pollution in developing countries.
In many cases, the development of COPD is not caused by just one factor, but rather smoking, polluted air and genetics interact to contribute to the development of the disease.
The diagnosis of COPD is usually based on lung function tests (such as spirometry), which assess a reduction in air flow rate. Although COPD cannot be cured, early detection and intervention can slow the progression of the disease. Treatment options usually include smoking cessation, lung function-improving medications, rehabilitation training, etc.
COPD is often associated with other health problems, such as cardiovascular disease, muscle dysfunction, and depression. These complications are common among people with COPD, so awareness and treatment to improve overall health are critical.
Mortality rates among COPD patients are often not due to breathing problems, but rather to these accompanying health issues.
According to statistics, COPD caused 3.2 million deaths in 2019, and this number is likely to rise further as the population ages and risk factors persist. Although the impact of COPD is widespread, prevention and health education will help reduce its morbidity and mortality.
We should think about: How can individuals and society work together to improve respiratory health in the process of preventing COPD and its complications?