As global public health needs increase, understanding the burden of disease becomes increasingly important. Among them, Disability-Adjusted Life Years (DALYs) is an effective indicator. This indicator takes into account not only the years of life lost due to premature death, but also the years of healthy life lost due to poor health or disability. By combining mortality and morbidity, DALYs provide an overall health status assessment tool.
Disability-adjusted life years (DALYs), as a measure of the overall disease burden, can help decision makers allocate public health resources effectively.
DALYs are a measure of society's burden of disease or disability in a population. The calculation method mainly combines life expectancy and health status adjustment. Specifically, DALYs are calculated using the following formula:
DALY = YLL + YLD
, where YLL stands for Years of Life Lost and YLD stands for Years Lived with Disability. This combination makes time central to assessing the impact of chronic disease.
YLL refers to the number of years of life lost due to premature death, while YLD refers to the number of years of life lost due to disability due to illness or disability. By using these indicators, public health experts are able to more fully assess the impact of a disease on society.
The YLD calculation formula is:
YLD = I × DW × L
, where I is the number of cases, DW is the disability weight, and L is the average period from onset to recovery or death.
The World Health Organization (WHO) used age weighting and time discounting before 2010 but has since stopped using these methods. Age-weighted theory states that years spent as young adults are more valuable than years spent in old age or childhood. The practice has drawn criticism because it may downplay health losses among the elderly and children.
While DALYs do not directly assign a monetary value to each person or condition, they can provide valuable guidance for allocating health resources. For example, vaccine cost-effectiveness analysis based on DALY can help countries or regions decide where to invest resources more effectively. For example, in Gambia, the cost of providing pneumococcal vaccination per DALY saved was approximately $670.
As of 2019, the global economic value lost due to stroke is estimated to be as high as US$2 trillion.
In an example of major global diseases, cancer and cardiovascular disease in Australia are the leading causes of healthy life years lost. Yet, despite these challenges, Australia has one of the highest life expectancy rates in the world.
In contrast, some parts of Africa, such as Zimbabwe, face more severe health challenges, such as typhoid and malaria, the prevalence of which directly affects the number of healthy years of local residents.
The term DALY was first developed by Harvard University for the World Bank in 1990 and later adopted by the World Health Organization in 1996. Since then, DALYs has become one of the key indicators for measuring the global health burden and has been widely used in many global health reports.
Although DALYs have gained wide acceptance in public health, there are also some critics who believe that this indicator is merely an economic assessment of human productivity. Supporters emphasize that the disability weight of DALYs considers the quality of a patient's life rather than just their ability to work, which is particularly evident when it comes to mental health issues.
We can see that DALYs, as an important tool for measuring health problems, can not only guide resource allocation, but also reveal the most pressing public health challenges. In the future, how can we use these indicators more effectively to address global health issues?