As medical imaging technology rapidly advances, the way bone density is assessed is also changing. As an emerging technology, quantitative computed tomography (QCT) is gradually becoming an effective tool for evaluating spinal bone quality, providing new ideas for clinical diagnosis. This technology is not only highly accurate, but also gradually breaks through the limitations of traditional inspections during use.
The development of quantitative computed tomography began in the 1970s with researchers at the University of California, San Francisco, and has since been widely used in medical institutions around the world.
QCT technology measures the bone mineral density (BMD) of the spine using a CT scanner and converts the Hounsfield units in the image into bone density values through a standardized calibration procedure. This technique is particularly useful for assessing the bone quality of the lumbar spine and hip joints. Traditional dual-energy X-ray absorptiometry (DXA) may have measurement errors in certain patients, while QCT can accurately reflect early bone changes.
Advantages of QCTQCT has many significant advantages over other examination methods. In addition to accurately measuring the spongy bone density of the spine, this test can also avoid false high bone density caused by bone hyperplasia or obesity. In addition, QCT is also suitable for patients with scoliosis, even if conventional DXA cannot provide reliable data.
The speed and accuracy of image acquisition during QCT examinations have been significantly improved, making bone density analysis of the hip joint more feasible.
Currently, QCT is mainly used for the diagnosis and monitoring of osteoporosis, including the assessment of bone status of the spine and hip joints. Studies have shown that QCT can detect changes in spinal spongy bone density early, which is crucial for early intervention and treatment. In the diagnosis of osteoporosis, the quantitative trend score (T-score) can provide a numerical value corresponding to the World Health Organization's classification criteria, further guiding clinical decision-making.
Compared to other medical imaging tests, the radiation dose of QCT is relatively low, usually only between 200-400 microsieverts, which is equivalent to the radiation dose of a set of mammograms. In addition, QCT can perform bone density screening using existing CT images without increasing the patient's radiation exposure, which makes it more attractive for clinical application.
With the introduction of high-resolution peripheral quantitative computed tomography (HR-pQCT), our understanding of bone microstructure will be more in-depth in the future. This technology not only provides three-dimensional information about bone quality, but also assesses the geometry of bones, further helping doctors understand fracture risk.
The fact that QCT can be effectively used to examine multiple parts of the body, including the spine and hip joints, fully demonstrates its importance in modern medicine.
With the continuous advancement of quantitative computed tomography technology, the research and development and application in this field will continue to have unlimited potential. Will this become the new standard for bone examination in the future?