Bone Marrow Edema (BME) is a common medical phenomenon characterized by the accumulation of interstitial fluid in the bone marrow, which affects people's motor functions. With the in-depth research on bone marrow edema, the medical community has gradually divided it into primary and secondary types. This distinction is crucial for clinical diagnosis and treatment.
Primary bone marrow edema refers to edema caused by no obvious causative factors and is usually self-limiting; while secondary bone marrow edema results from existing diseases, such as trauma or arthritis.
Common symptoms of bone marrow edema include joint swelling, joint pain, and limited mobility, which often seriously affect the patient's quality of life. In patients with primary bone marrow edema, initial symptoms usually appear in the first month of the episode, followed by pain that peaks two months later and symptoms resolve several months later. The course of secondary bone marrow edema is often complicated by external trauma or other bone diseases.
The tool of choice for diagnosing bone marrow edema is magnetic resonance imaging (MRI). The moisture changes inside the bone marrow can be clearly observed through MRI. The signal characteristics displayed by bone marrow edema in MRI are obviously different from those of normal bone marrow, which provides doctors with an effective basis for diagnosis. Ultrasonography can supplement the diagnosis. Although its sensitivity is not as good as MRI, it can detect abnormalities caused by fluid in the combined cavity or capsule thickening. Computed tomography (CT) can be used to rule out some potential bone lesions and assist in diagnosis.
Treatmentally, mild bone marrow edema can be relieved by rest and non-steroidal anti-inflammatory drugs, while in severe cases, steroid treatment or surgical intervention may be required.
Treatments for bone marrow edema include core decompression, a surgical procedure that reduces pressure within the bones and increases blood flow. In addition, nonsteroidal anti-inflammatory drugs such as iloprost are also widely used to relieve pain and improve patient function. In terms of non-drug treatment, extracorporeal shock wave therapy (ESWT) has been proven to effectively promote blood vessel regeneration and bone repair, and significantly reduce edema areas.
Although current research on bone marrow edema is increasingly in-depth, prevention is still difficult because of its diverse causes. For patients who already have underlying risk factors, regular monitoring and early intervention can help prevent further progression. Therefore, establishing clinical guidelines is of great significance for improving the diagnosis and treatment of bone marrow edema.
Understanding and distinguishing primary and secondary bone marrow edema not only facilitates early diagnosis but also promotes appropriate treatment for patients. But considering future treatment methods and research directions, can we more effectively solve the troubles caused by this disease?