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Imitation of the Power of Nature: How do supramolecular systems learn the wisdom of biomolecules?
In the vast universe of chemistry, supramolecular chemistry, as a brand new field, has shown extraordinary charm.It not only involves a system composed of molecules, but also focuses on weaker non-covalent interactions such as hydrogen bonds, metal coordination and hydrophobic interactions, which are the basis of life processes.These forces have led to the combination and recombination of molecules, allowing us to have a glimpse of the essence of life, and thus aroused interest in the guidance of supramolecular biology.
The noncovalent action of supramolecular chemistry is key to understanding many biological processes that rely on these forces structures and functions.
The history of supramolecular chemistry can be traced back to the 19th century, when Johnnis Diderick van der Waals first proposed the concept of intermolecular interactions.On this basis, Nobel Prize winner Hermann Emil Fisher proposed the theory of "lock and key" between enzymes and substrates in 1894, which became the cornerstone of molecular recognition.With the advancement of science, our understanding of hydrogen bonds and other non-covalent interactions has gradually deepened, especially the clear explanation of DNA structure, which has brought research in this field into a new era.
Scientists across the ages have pushed supramolecular chemistry to a new peak through a series of innovative research.
In recent years, supramolecular chemistry has been increasingly used, including materials technology, catalysis and medicine.In materials technology, the process of supramolecular self-assembly is used to develop new materials, while catalysis uses non-covalent interactions to design the binding of the reaction substrate.More dramatically, the design of supramolecular biomaterials provides new possibilities for many platforms that adjust mechanical, chemical and biological properties.
In the field of biology, the development of supramolecular systems has significant significance for the creation of functional biological materials and therapies.These designs are based on the principles of supramolecular chemistry and can create diverse ion channels to control the inlet and exit of key ions such as sodium and potassium, which is crucial for cellular function.
These platforms can not only improve the performance of existing biomaterials, but also lead the design and development of future drug therapies.
Like the operating principles of nature, each system is composed of basic units.The supramolecular system is based on various known structural and functional modules, which can be used to synthesize more complex and functional architectures.A large number of studies have shown that these supramolecular systems have good tunability, such as applications in optical, catalytic and electronic properties.
And these systems that simulate natural mechanisms, such as molecular machines, can move at a very small scale, opening up a series of new technological applications.These molecular machines are not only part of nanotechnology, but can also be designed and synthesized according to needs, paving the way for future technological exploration.
These biologically inspired structures can not only drive scientific progress, but also help us understand the operation of biological models.
Combined with chemistry, physics and biology, the development of supramolecular chemistry is like the creativity of nature, prompting scientists to explore new possibilities.From materials science to drug research and development, supramolecular systems are obviously one of the key areas of future technology.In this rapidly evolving field, we can’t help but ask: Where will these supramolecular systems that simulate natural intelligence lead us?
