In the field of biology, the regulation of the internal environment is the key to maintaining stable functions of every living system.This phenomenon is called homeostasis. From ancient times to the present, scientists' understanding of this concept has been deepened, and Claude Bernard's contribution cannot be ignored.In 1849, Bernard described the regulation of the internal environment, which laid an important foundation for later biological research, especially in understanding how organisms resist external changes.
Stable state is the stable state of physical and chemical conditions within a biological system that can remain relatively stable when the external environment, diet or activity level changes.
Specifically, variables involved in steady state include body temperature, internal liquid equilibrium, pH, etc. These indicators need to be maintained within a preset range.For example, the body temperature regulation system involves multiple monitoring mechanisms that work together to adjust physiological states and ensure that various biological reactions can be performed under the most suitable conditions.
Maintenance of steady state relies on a complex set of regulatory mechanisms, each of which includes at least three interdependent components: receiver, control center, and effector.The receiver is responsible for monitoring and responding to changes in the internal and external environment, while the control center is responsible for setting the maintenance range of variables and issuing corresponding instructions to the effector according to the receiver's signal.These effectors can be muscles, organs, or glands, through which the system is adjusted back to homeostasis.
For example, when glucose levels in the body are too high, the beta cells of the pancreas sense this change and secrete insulin to encourage the liver and other tissues to absorb glucose and store it as glycogen, thereby reducing blood sugar levels.This process demonstrates the biological basis of internal environmental regulation and its power to survive.
The mechanisms that regulate the internal environment are not limited to single variables, but maintain the stability and adaptability of life through synergy.
Claude Bernard's research is not only groundbreaking in physiology, but also emphasizes the importance of the brain in homeostasis regulation.He believes that homeostasis is not only the basis of cell survival, but also a necessary condition for higher neurological functions.This view was further consolidated by British physiologist Joseph Barcroft in 1932, who pointed out that sound brain function requires a stable internal environment as a guarantee.
The concept of steady state is not static, it emphasizes changes and adaptation of the internal environment.For example, the human body will initiate different physiological reactions at high or low temperatures to maintain the core temperature in the body.In cold environments, vasoconstriction reduces heat loss, while in hot environments, it cools down through sweating.This regulatory behavior is a systemic reaction that reflects the ability of organisms to adapt to the environment.
With the advancement of technology, the concept of steady state is gradually expanding to other fields.Control systems (such as thermostats) are technically similar to the steady-state mechanism of organisms, which is also an important reason why the term "cybernetics" is proposed.Humans are not only restricted by biology, but also can apply these theories to self-regulate and adapt.
The significance of steady state far exceeds biology, and it reminds us how internal balance should be maintained when facing environmental challenges, whether in the biological body or outside of the technical system.
Overall, Claude Bernard's discovery of internal environmental steady state not only laid an important foundation in biology, but also triggered new explorations in related disciplines.In the face of the ever-changing ecological environment and technological progress, we should perhaps think about how to achieve stability of the internal environment and harmony of the external environment while maintaining human survival?