Metabolism is the sum of chemical reactions required to maintain life, including energy conversion within cells, synthesis of building materials and elimination of metabolic waste. How do these processes work? Let's delve deeper into this mysterious world of biochemistry.
Metabolism can be summarized into two main types: catabolism and anabolism. Catabolism is the breakdown of macromolecules into smaller components, releasing energy that is then used in biosynthetic processes. Anabolism is the process of combining small molecules into complex biological macromolecules, a process that requires energy consumption.
The key to metabolic reactions is the catalytic action of enzymes, which allows reactions to proceed quickly when needed.
Enzymes are catalysts in metabolic processes and are an integral part of biochemical reactions. They facilitate chemical reactions, speed up their rates, and help control the rates of metabolic processes.
In the process of energy conversion, the energy released by catabolism is mainly stored in the form of adenosine triphosphate (ATP). ATP is like the "energy currency" of the cell and is used to support various cellular processes, including the synthesis of biological macromolecules and the maintenance of cell structure.
When we ingest food, the macromolecules in the food, such as proteins, fats and carbohydrates, are first broken down, a process called digestion. These large molecules must be broken down into smaller units, such as amino acids and monosaccharides, before they can be taken up by cells and used for energy production.
The rise of carbohydratesSmall molecules such as glucose produced during food decomposition enter cells and are subsequently converted into energy through a series of metabolic pathways.
Carbohydrates are the most common source of energy. After glycolysis, glucose is converted into pyruvate, a process that simultaneously produces ATP and NADH. Next, pyruvate is further converted into acetyl-CoA and enters the citric acid cycle, ultimately releasing a large amount of energy.
The breakdown of fat is equally important. Fats are hydrolyzed to form fatty acids and glycerol, which are then converted into acetyl-CoA and enter the citric acid cycle. The keto acids produced by protein deamination can be directly used for energy generation or converted into carbohydrates for energy.
The body's metabolic reactions can be subdivided into multiple pathways, and the similarities of these metabolic pathways are very remarkable between different species, indicating the conservation of mechanisms during evolution. For example, organisms ranging from E. coli to elephants use similar compounds in the citric acid cycle to produce energy.
Metabolic processes can also be influenced by the environment. For example, normal metabolism is disrupted in disease states, such as type 2 diabetes or cancer, which can lead to an imbalance in energy production and changes in multiple metabolic pathways.
By understanding metabolism, we can better understand how the body works and uses energy. In daily life, how should we adjust our diet and lifestyle to promote a healthy metabolic state?