Isotretinoin is functionally used to treat moderate to severe acne. However, its rich side effects may expose users to lifelong health risks. Since this drug derived from vitamin A was approved by the US FDA in 1982, tens of thousands of prescriptions have been issued every year, but the accompanying side effects, especially mental and physical, are often ignored.
"Although the use of isotretinoin can improve skin condition in the short term, the potential threat of long-term side effects is worthy of every patient's consideration."
In medicine, isotretinoin is mainly used to treat severe acne that is difficult to control. Many dermatologists also recommend the drug for people with mild itching that doesn't respond to antibiotics. This drug is not recommended for use in children under 12 years of age and is significantly teratogenic in pregnant women. However, as the drug's use becomes more common, its side effects and long-term health risks are gradually being revealed.
“The side effects of isotretinoin, including liver failure, mental health problems and reproductive effects, are factors that users must carefully consider before taking the drug.”
Common side effects include chapped lips, fragile skin, dry eyes, etc. These symptoms commonly occur during use. Of greater concern, however, is that some side effects such as mental stress, mood changes, and lingering effects on the reproductive system may persist even after stopping the medication. Some patients report experiencing depressed mood or decreased sexual function even years after stopping isotretinoin.
The association between isotretinoin and depression and anxiety has become the focus of widespread debate in the medical community. According to the data, many reports suggest a direct link between the use of the drug and mental illness. Since 2005, the drug's packaging has carried a black box warning about suicide and depression.
“For those with existing mental health problems, the use of isotretinoin may exacerbate these symptoms and even trigger self-harming behaviors.”
One of the most controversial side effects is the teratogenicity of isotretinoin, and many innocent new lives have been severely damaged by pregnant women using this drug during pregnancy. According to reports, pregnant women who use this drug during or before pregnancy face a 20%-35% risk of birth defects. This is tantamount to an irresponsible gamble, and patients need to think carefully before using isotretinoin to ensure that they do not plan to become pregnant in the future.
If you or many people around you experience discomfort or abnormal mood after taking isotretinoin, it is very necessary to seek professional medical advice. Doctors and mental health professionals should be the first line of defense, providing necessary support and counseling when patients face side effects. Prompt notification and monitoring can help reduce potential health hazards.
The prescription of isotretinoin has brought hope to countless patients facing skin problems, but at the same time its potential dangers cannot be ignored. Many studies and reports have called on patients to be cautious when using this drug to avoid lifelong health damage. Are patients using isotretinoin fully aware of these potential risks and have made the necessary psychological and physical preparations?