The miracle of two-photon absorption: How do we absorb two photons simultaneously in the microscopic world?

In modern physics, two-photon absorption (TPA) is an exciting phenomenon that involves the absorption of two photons at the same time, usually resulting in the excitation of atoms or molecules from their ground state to A higher electron energy level. The understanding of this process is crucial for the exploration of the microscopic world, and its characterization plays a key role in many advanced technologies, including imaging and the development of optical materials.

Two-photon absorption is known as a nonlinear optical process that is significantly different from the traditional one-photon absorption process.

Basic principles of two-photon absorption

Two-photon absorption refers to the process by which molecules or atoms are excited by the simultaneous absorption of two photons. The two photons can have the same or different frequencies. Two-photon absorption occurs when the sum of the energy of the two absorbed photons is equal to or greater than the excitation energy of the molecule or atom. The characteristic of this process is that its occurrence probability is proportional to the square of the light intensity, so it is often regarded as a nonlinear optical phenomenon.

The probability of two-photon absorption is proportional to the square of the light intensity, which shows its nonlinear nature.

History of Two-Photon Absorption

The concept of two-photon absorption was first proposed in 1931 by Maria Goeppert Mayer. This phenomenon was not experimentally verified until the advent of laser technology in the 1960s. As the research deepened, scientists discovered that two-photon absorption is found in many materials and systems, including Eurasian mixed crystals and semiconductors such as potassium chloride.

Techniques for measuring two-photon absorption

There are several methods for measuring two-photon absorption, including two-photon excited fluorescence (TPEF), Z-scan, and self-diffraction techniques. Because two-photon absorption is a third-order nonlinear optical process that relies on high light intensities, pulsed lasers are often used to facilitate related experiments.

The key to two-photon absorption is that it requires a very strong light source, which makes pulsed lasers the first choice for research.

Application prospects of two-photon absorption

The applications of two-photon absorption technology in drug delivery, in vivo imaging and optical writing are extensive and diverse. For example, in biological imaging, two-photon excitation can be used to non-invasively observe the internal structure of cells with higher depth of field and resolution than traditional single-photon techniques.

Future Research Directions

Currently, the research focus of two-photon absorption includes improving the two-photon excitation efficiency of materials and developing new materials that are expected to revolutionize technology. By gaining a deeper understanding of the fundamental principles of two-photon absorption, scientists hope to develop new types of optical components and systems to further advance technology in this field.

Future research will not only improve the understanding of two-photon absorption, but may also lead to entirely new technologies and applications.

Conclusion

As a wonderful nonlinear optical process, two-photon absorption has shown great potential and broad application prospects in many fields. Although our understanding of this phenomenon is still growing, what breakthroughs and advances will future research bring?

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