In today's fast-paced society, many people ignore the importance of sleep health, but for some people, the challenge of sleepiness is an unavoidable shadow in daily life. Idiopathic Hypersomnia (IH) is a neurological disorder characterized by excessive daytime sleepiness and prolonged sleep, but its cause remains unknown. In such a situation, the patient's quality of life will be seriously affected, affecting his ability to work and study normally.
The impact of sleepiness may be beyond your imagination, and may even threaten the patient's safety and social functioning.
The main symptoms of narcolepsy include: Prolonged excessive daytime sleepiness, and patients often feel unable to wake up even if they get enough sleep at night. Many patients experience "sleep inertia" in daily life, that is, they feel extremely sleepy when they first wake up, and even have the urge to fall asleep again. In addition, along with the symptoms of "brain fog", patients often experience problems such as difficulty concentrating, confusion, and memory impairment.
These symptoms may further affect work performance, memory, learning ability, and other cognitive functions.
Due to the lack of clear biomarkers, doctors often need to rule out other conditions that cause daytime sleepiness to diagnose narcolepsy. This may require multiple tests, noting that in some cases an additional diagnosis of narcolepsy needs to be considered, even if other specific causes of narcolepsy are present. This makes correctly diagnosing narcolepsy more complicated.
During the diagnosis process, research has shown that daytime sleepiness in narcolepsy patients is more likely to be related to psychological fatigue rather than physiological sleepiness.
Currently, treatments for narcolepsy often focus on symptom management. While there are already some drugs for narcolepsy, such as the FDA-approved low-sodium oxybarbic acid (Xywav), others present varying degrees of challenges in tailoring efficacy and tolerability. For some patients, stimulants such as dextroamphetamine and dextroamphetamine are the main treatment options, but these drugs are often less effective in people with narcolepsy than in people with narcolepsy.
Even so, finding more personalized treatment options based on the diversity of narcolepsy patients will remain an important goal for future research.
Narcolepsy can have a profound impact on a patient’s quality of life. Unable to effectively manage daytime sleepiness, patients often need to adapt to new lifestyles that avoid working or driving in potentially dangerous situations. This also means that patients may need to make compromises in work, social life, etc. to adapt to their condition.
As research into narcolepsy deepens, the clinical community's understanding and definition of this symptom will continue to improve. However, challenges remain, particularly in diagnosis and treatment. According to current research, patients and their families not only need better medical resources but also extensive social support for sleepiness that often feels uncontrollable. This makes it necessary for us to think about how to promote the understanding and treatment of related diseases in the future to improve the quality of life of patients?