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The Revolution of ACE Inhibitors: Why Doctors Recommend They to Fight Diabetes Complications?
In modern medicine, ACE inhibitors (angiotensin-converting enzyme inhibitors) have become important weapons in the fight against hypertension and heart failure. However, as research deepens, such drugs have been found to be particularly beneficial to diabetics and can effectively reduce the risk of complications. This article will explore the mechanism of action of ACE inhibitors and their application in the treatment of complications of diabetes, especially how to protect patients' lives by regulating blood pressure and improving renal function.
Principle of action of ACE inhibitors
ACE inhibitors mainly achieve their efficacy by inhibiting the activity of angiotensin-converting enzymes. The main function of this enzyme is to convert angiotensin I into angiotensin II, a powerful vasoconstrictor; at the same time, it is also involved in the degradation of bradipose, a peptide that helps dilate blood vessels. When ACE inhibitors are used, the production of angiotensin II in the body is reduced, while Braditin levels rise, further helping to dilate blood vessels and lower blood pressure.
The dual effects of this drug not only reduce the heart's oxygen demand, but also improve overall cardiovascular health.
ACE inhibitors and complications of diabetes
Complications of diabetes, especially nephropathy (diabetic nephropathy), have a significant impact on the patient's quality of life. ACE inhibitors can reduce the filtration pressure of the renal tubules and reduce tubular damage caused by hypertension. Several studies have shown that there is a clear association between the use of ACE inhibitors and the slowdown in progress in diabetic nephropathy.
Diabetic patients with ACE inhibitors generally have lower renal function than patients without medication.
Doctor's recommendations and practical applications
According to clinical guidelines, ACE inhibitors are often recommended as the first line of treatment for hypertension, especially in patients with diabetes. When choosing a treatment plan for a patient, doctors will consider their age, health status, and their response to other drugs. For best results, ACE inhibitors are sometimes used in combination with other antihypertensive drugs, such as thiazide diuretics.
Side effects and precautions
Although ACE inhibitors are effective in treatment, they may also have some side effects, the most common of which include dry cough, hyperkalemia, and hypotension. Therefore, it is especially important for doctors to carefully monitor the patient's renal function and electrolyte balance when prescribing such drugs. This is especially important for patients with renal artery stenosis.
For most patients, after a period of adaptation, the side effects of ACE inhibitors are controllable and can achieve long-term health benefits.
Future research and prospect
Along with the ongoing research, the medical community has gained a deeper understanding of the potential applications and long-term effects of ACE inhibitors. Future research directions may focus on the effects of these drugs on other chronic diseases, especially the reduction in the risk associated with heart disease and stroke. ACE inhibitors are not just therapeutic tools for hypertension, but their role in overall disease management may continue to expand as the times progress.
Will the revolution in ACE inhibitors change the treatment strategies for diabetic patients?
