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The Secret of Blood Closure: Why do some people become the "winners" of blood clots?
Tradicles are a health problem that plagues many people, and some people seem to never face this problem.According to research, abnormal blood clotting can lead to blood clots, i.e. blood clots in blood vessels. This condition occurs without obvious reasons and is called thrombosis.It is worth noting that about 50% of people who have experienced thrombosis events can actually find abnormal blood clotting during blood tests, but most people only develop thrombosis if there are additional risk factors.
Thrombosis is closely related to deep venous thrombosis (DVT) and pulmonary embolism (PE), which are called venous thromboembolism (VTE).
DVT usually occurs in the legs and is characterized by limb pain, swelling and redness; this blood clot, if sheds, may migrate to the lungs, causing severe dyspnea and chest pain.Therefore, the generation of such thrombosis is not only related to personal health, but also may lead to life danger.
Symptoms and symptoms of thrombosis
As mentioned earlier, common signs of DVT include swelling, pain and redness in the legs.The formation of a thrombus can affect not only the legs, but also veins in other parts, such as the brain or kidneys, leading to wider health problems.Some studies have shown that certain hereditary thrombosis may increase the risk of arterial thrombosis, which is also the main culprit of heart disease and stroke.
Latest data suggest that certain forms of genetic thrombosis are associated with an increased risk of arterial ischemic stroke.
The causes of thrombosis
Thrombosis can be divided into two categories: congenital and acquired.Congenital thrombosis refers to a situation that has existed since birth, while acquired thrombosis occurs with age or due to the influence of certain conditions.
Congenital Thrombosis
The most common congenital thrombosis is caused by excessive activity of coagulation factors, which include variations in the factor V Leiden and prothrombin genes caused by mutations in the F5 gene.These mutations lead to abnormal increases in the blood coagulation factors, which increase the risk of blood clotting.
Blood type is also an important factor affecting the risk of thrombosis. Other blood types are 2 to 4 times higher than type O.
Acquired Thrombosis
Acquired thrombosis is usually related to lifestyle factors, including obesity, smoking, long-term bed rest, etc.Certain autoimmune diseases, such as antiphospholipid syndrome, cause antibodies in the body to attack cell membrane components, resulting in the formation of thrombosis.
Cancer is another common cause of increased risk of thrombosis, especially when tumors spread to other parts of the body.Activation of cancer cells can promote the initiation of the coagulation system and further increase the chance of thrombosis formation.
Diagnosis of thrombosis
When a thrombosis test is performed, doctors usually perform detailed blood tests, which may include a complete blood count, a clotting time test, and a genetic mutation test.These tests can help identify potential thrombotic risk factors.
The latest guidelines recommend that thrombosis testing should be delayed after thrombosis is diagnosed to ensure the accuracy of the test results.
Treatment Plan
At present, there are currently no specific treatments for thrombosis. Long-term use of anticoagulants (such as warfarin) can reduce the chance of reappearing thrombosis in high-risk patients.Doctors will decide on the treatment options based on the patient's specific circumstances and potential bleeding risk.
For female patients with thrombosis who want to get pregnant, they should not usually use warfarin in the early stages of pregnancy, but instead choose alternative drugs such as low molecular weight heparin.
Thinking and future prospect
Although the causes of thrombosis are complex and diverse, many risk factors can be managed by adjusting their lifestyle, such as diet control, regular exercise, etc.With the advancement of medical technology, the detection and treatment methods for thrombosis are also being improved.So, how can we prevent the formation of thrombosis more safely and make ourselves the "winner" of this thrombosis battle?
