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The secret weapon of anti-nausea drugs: What ingredients can defeat vomiting and nausea?
In life, nausea and vomiting are common troubles that people face. Whether it is due to motion sickness, chemotherapy or other food poisoning, these nauseating feelings may make people unable to live normally. However, the advent of anti-nausea drugs has given many people hope. These medications can effectively relieve these problems and allow people to return to their daily lives.
Under what circumstances do anti-nausea medications work best?
Anti-nausea drugs are mainly divided into several different types, including 5-HT3 receptor antagonists, dopamine antagonists, NK1 receptor antagonists, antihistamine drugs and cannabinoids, etc. Each of these drugs has different mechanisms of action. .
5-HT3 receptor antagonist
This type of drug can effectively block serotonin receptors in the central nervous system and digestive tract, and is suitable for nausea after surgery and vomiting caused by chemotherapy. For example:
- Dolasetron (Anzemet)
- Granisetron (Kytril, Sancuso)
- Ondansetron (Zofran)
- Tropisetron (Setrovel, Navoban)
- Palonosetron (Aloxi)
Side effects of these medications include constipation, dry mouth, and fatigue.
Dopamine antagonist
Dopamine antagonists are mainly used to treat nausea and vomiting caused by cancer, radiation sickness, anesthetics, etc. Common drugs include:
- Amisulpride (Barhemsys)
- Domperidone (Motilium)
- Droperidol
- Olanzapine (Zyprexa)
- Metoclopramide
However, these drugs can also cause side effects such as muscle cramps and anxiety.
NK1 receptor antagonist
This type of drug, such as Aprepitant, is particularly suitable for severe vomiting caused by chemotherapy. Studies have shown that it is more effective when used together with 5-HT3 antagonists.
Antihistamine drugs
This type of medication is effective for many conditions, including motion sickness and morning sickness during pregnancy. Common medications include:
- Cinnarizine
- Cyclizine
- Diphenhydramine (Benadryl)
- Dimenhydrinate (Gravol)
In addition, many antihistamine drugs can also block cholinergic receptors and enhance the anti-nausea effect.
Cannabinoids
For some patients, cannabinoids such as Nabilone and Dronabinol are used to combat nausea and vomiting caused by chemotherapy, although they can cause side effects such as changes in perception, dizziness and loss of coordination.
Other drugs
Two less common but effective drugs include Dexamethasone and Trimethobenzamide. In addition, natural ingredients such as ginger are also thought to be effective in relieving nausea.
Preliminary clinical data suggests ginger may be effective in treating nausea or vomiting in a variety of settings.
These different types of anti-nausea medications are constantly being developed and improved, and the goal of the medical community is to find appropriate solutions for all concerned. When nausea and vomiting strike again, what will you do to combat the discomfort?
