Cerebral Arteriovenous Malformation (CAVM) is an abnormal blood vessel structure, usually located in the brain, that causes abnormal connections between arteries and veins. This condition can cause a variety of potential symptoms and have a significant impact on the patient's quality of life. Many patients may not experience any obvious symptoms when they are diagnosed, but when the problem becomes severe, they may face extremely serious health risks.
The most common problems associated with brain AVMs include headaches and seizures, and there may also be neuropathies such as nerve compression and hemiplegia.
Symptoms of brain arteriovenous malformations vary from person to person, but some common symptoms include persistent headaches, seizures, increasing weakness, loss of sensation, and vision changes. Some patients may even experience bleeding within the brain, which is one of the most dangerous consequences of brain arteriovenous malformations. According to statistics, bleeding is often the first symptom in more than half of patients with cerebral arteriovenous malformations.
When a brain arteriovenous malformation ruptures, it may cause symptoms such as loss of consciousness, sudden severe headache, nausea, vomiting, and blurred vision.
Bleeding in the brain can not only cause direct nerve damage, but can also cause other serious problems, such as seizures and loss of facial or limb movement. Studies show that rupture of cerebral arteriovenous malformations can lead to a mortality rate of up to 29%, and only 55% of patients can live independently. These data undoubtedly demonstrate the potential risk of cerebral arteriovenous malformations.
The annual discovery rate of cerebral arteriovenous malformations is about 1 case per 100,000 people per year, and the incidence rate in adults is about 18 cases per 100,000 people. The incidence rate in men is higher than that in women.
Diagnosis of cerebral arteriovenous malformations usually relies on neuroimaging, which includes computed tomography (CT), magnetic resonance imaging (MRI), and cerebral angiography. CT scans are the most commonly used initial diagnostic tool, while MRI can provide more detailed information on the location and shape of lesions. For the evaluation of brain arteriovenous malformations, radioactive substances can also be injected to further understand the structure of blood vessels.
According to the Spetzler-Martin grading system, the severity of cerebral arteriovenous malformations can be graded from 1 to 5 to assess the patient's risk of neurological deficit after surgery.
Treatment for cerebral arteriovenous malformations depends on their size, location and whether bleeding has occurred. For patients with sudden bleeding, treatment focuses on restoring vital signs. Anti-epileptic drugs are often used to control seizures, and neurosurgery is sometimes required to remove malformed blood vessels.
In the case of small arteriovenous malformations, radiosurgery such as gamma knife is widely used to control the growth of cerebral arteriovenous malformations and the risk of bleeding.
However, all treatment options come with certain risks, such as neurological impairment. Therefore, a patient’s treatment plan needs to be formulated under the guidance of medical experts based on their specific circumstances.
The prognosis of cerebral arteriovenous malformations varies, with the risk of bleeding being the main consideration. Long-term observation shows that the average annual bleeding rate is about 4%. This means that patients who are diagnosed earlier are more likely to bleed as they age.
Research has found that without any treatment, cerebral arteriovenous malformations may affect the patient's life.
As understanding of brain arteriovenous malformations increases, researchers are exploring more effective treatments and risk assessment methods. Will future medical advances improve the quality of life of patients with cerebral arteriovenous malformations?