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Magic from Plants: How Genetics Fight Cancer and Inflammation?
In today's generation, the treatment of cancer and inflammation-related diseases has been a challenge for the global medical community, and plant compounds in nature may provide hope for finding new treatments. Among many plant compounds, Genistein has attracted much attention due to its multiple biological activities and potential therapeutic uses. This article will delve into the origin, structure and specific mechanisms of how genes affect human health.
What are genetic factors?
Gene is a plant endogenous compound that belongs to the isoflavones class and is mainly known for its anti-tumor and anti-inflammatory properties. The compound was first extracted from the plant Genista tinctoria in 1899 and has the chemical molecule C15H10O5. The structure of the genetic factor was confirmed in 1926 and chemically synthesized in 1928.
Natural sources
Genetic factors not only exist in goldenrod roots, but also widely exist in a variety of plants, such as soybeans, broad beans, kudzu root, etc. These plants are an important food source and also exhibit therapeutic properties in traditional medicine.
Genes are considered to be the major secondary metabolites of clover (Trifolium) and soybean (Glycine max).
Biological effects of genetic factors
The biological activity of genetic factors is not limited to its function as an antioxidant and an insecticide. Research shows that it interacts with estrogen receptors in plants and animals, causing estrogen-like effects. Various biological reactions caused by genetic factors include:
- Full agonists act on the beta estrogen receptor (ERβ)
- Partial agonists act on the alpha estrogen receptor (ERα)
- Influences various intracellular signaling pathways
- Importance in the activation reaction of fatty acid peroxidase
Potential to fight cancer
The potential of genetic factors as anti-cancer drugs is gradually gaining attention. Multiple studies have shown that it can inhibit enzymes related to tumor growth, such as tyrosine kinase (Tyrosine Kinase), and act as an anti-angiogenic agent to curb the spread of tumors. In addition, genetic factors have been proven to have inhibitory effects on various cancers such as prostate cancer and breast cancer at specific doses.
The main mechanisms of action of genetic factors include inhibiting cell division and promoting apoptosis of cancer cells.
Anti-inflammatory effect
Genetic factors also exhibit anti-inflammatory properties and regulate vascular inflammation, a biological mechanism thought to play an important role in cardiovascular diseases such as arteriosclerosis. This property makes it a potential treatment option that can help improve health problems caused by inflammation.
Risks and precautions of genetic factors
Despite the potential of genetic factors, there are certain risks. At high doses, it can be toxic to normal cells and carries a risk of causing hemolytic anemia. Additionally, some studies suggest that genetic factors may interfere with typical antiestrogen therapy, resulting in reduced efficacy.
For pregnant women, the intake of genetic factors may increase the risk of leukemia in their babies, which requires a high degree of vigilance.
Thinking about future possibilities
Research is ongoing around genetic factors to explore their potential clinical applications, especially in the treatment of cancer-related diseases. These findings not only bring hope to cancer patients, but also make us full of imagination about the therapeutic effects of natural plant compounds. Could genetic factors be an important option in future cancer treatments?
