JAMA Network Open | 2021
Evaluation of Attention-Deficit/Hyperactivity Disorder Medications, Externalizing Symptoms, and Suicidality in Children
Abstract
Key Points Question Are there associations among attention-deficit/hyperactivity disorder (ADHD) pharmacotherapy, externalizing symptoms, and childhood suicidality (ie, ideation or attempts)? Findings In this cohort study of 11 878 children aged 9 to 10 years at baseline, externalizing symptoms showed expected associations with suicidality. ADHD pharmacotherapy was associated with less suicidality in children with externalizing symptoms, specifically among those with substantial symptoms burden, both at the baseline and 1-year follow-up assessment. Meaning These findings suggest that in children with substantial externalizing symptoms, ADHD medication use may be associated with less suicidality, in addition to its known clinical benefits in treating externalizing symptoms.