JAMA Network Open | 2021
Assessment of Hearing Screening Combined With Limited and Expanded Genetic Screening for Newborns in Nantong, China
Abstract
Key Points Question Is the modified newborn genetic and hearing screening feasible in China? Findings In this population-based cohort study including 32\u2009512 infants, incorporating the limited and expanded genetic screening into physiological screening was associated with identifying 31 newborns with hearing loss missed by the conventional hearing screening, providing etiologic information to 1299 participants, and targeting 517 children at risk of late-onset hearing loss to improve prevention. Meaning Large observational studies are needed to evaluate the cost-effectiveness and long-term benefits of integrated genetic and hearing screening programs.