JAMA Network Open | 2021
Effect of Immediate Implant-Based Breast Reconstruction After Mastectomy With and Without Acellular Dermal Matrix Among Women With Breast Cancer
Abstract
Key Points Question Does acellular dermal matrix (ADM) in implant-based breast reconstruction reduce reoperation rates for women having immediate implant-based reconstruction in the setting of breast cancer treatment? Findings In this randomized clinical trial comparing implant-based breast reconstruction with and without ADM among women with primary breast cancer, use of ADM in reconstruction did not yield fewer reoperations. Meaning Women with breast cancer considering immediate implant-based breast reconstruction should anticipate several reoperations; clinics should inform patients about the limited evidence of benefit of ADM-assisted breast reconstruction.