Photochemical C-H Amination of Ethers and Geminal Difunctionalization Reactions in One Pot.

Abstract

A mild, atom-economic and metal-free α-C-H amination of ethers using relatively stable nonafluorobutanesulfonyl azide as the aminating reagent resulting in N-sulfonyl hemiaminals is reported. This enables unprecedented C(sp3) difunctionalization reactions leading to diverse functionalized amino group-containing compounds starting from simple ethers in one-pot.