Brain and Behavior | 2021
Lamotrigine for acute bipolar depression: An exploratory item‐level analysis
Abstract
Lamotrigine is used to treat bipolar depression despite inconsistent evidence. Here we present the results of an exploratory item‐level analysis of pooled data from five randomized placebo‐controlled trials of lamotrigine for acute bipolar depression. The goal was to determine if certain depression scale items were more responsive to lamotrigine treatment.