ChemCatChem | 2019
A Divergent Duo: Palladium Catalyzed Carboamination in Enantioselective Desymmetrization and Regiodivergent Catalysis
Abstract
We describe a regiodivergent synthesis of pseudo‐C2‐symmetrical and pseudo‐meso bis‐indoline scaffolds from norbornadiene and substituted o‐iodo‐anilines. The Pd(0)/Josiphos system enables the highly regioselective catalyst controlled carboaminations required for the two step synthesis of the scaffolds.