Initial experience with high‐volume plasma exchange in patients with acute liver failure

Abstract

High‐volume plasma exchange (HVPE), defined as an exchange of 8 to 12\u2009L per day per procedure or 15% of the ideal body weight with fresh frozen plasma, has shown promising results in improving the survival of patients with acute liver failure (ALF). However, clinical evidence is limited. The aim of this study was to report our initial experience using HVPE as a bridge treatment in patients with ALF.