Journal of Surgical Oncology | 2019
Association of preoperative monocyte‐to‐lymphocyte and neutrophil‐to‐lymphocyte ratio with recurrence‐free and overall survival after resection of pancreatic neuroendocrine tumors (US‐NETSG)
Abstract
Preoperative systemic inflammatory response plays a crucial role in tumorigenesis, progression, and prognosis; and neutrophil, monocyte, and lymphocyte counts serve as important biomarkers. An altered monocyte‐to‐lymphocyte ratio (MLR) and neutrophil‐to‐lymphocyte ratio (NLR) has been reported to be associated with a favorable prognosis for certain hematologic malignancies and breast cancer. The aim of this study was to investigate the prognostic significance of MLR, NLR in patients with resectable PNETs.