Evaluation of efficacy and safety of single-incision sling versus transobturator sling in women with stress incontinence and intrinsic sphincter deficiency

Abstract

Urethral intrinsic sphincter deficiency (ISD) is associated with severe urine leakage and a higher risk of sling failure. The aim of this study is to evaluate the efficacy and safety of single-incision slings (SISs) versus transobturator slings (TOSs) in such patients. Patients who had stress incontinence and ISD who underwent SIS or TOS procedures from 2010 to 2017 were retrospectively reviewed. The objective and subjective cure rates and surgical adverse events were compared between different slings. Objective cure was defined as no stress urine leakage with a comfortably full bladder. Subjective cure was determined by the patient’s satisfaction. Incontinence-related symptom distress and quality of life were evaluated using the short forms of the Urogenital Distress Inventory (UDI-6) and Incontinence Impact Questionnaire (IIQ-7). Among 111 patients, 37 underwent SIS and 72 underwent TOS with a median follow-up of 21 (range: 12–72) months and 24 (range: 14–84) months (p\u2009=\u20090.265). For both groups, the UDI-6, IIQ-7, and 1-h pad test all significantly improved after surgery (all p\u2009<\u20090.001). The objective and subjective cure rates were comparable after SIS and TOS procedures (objective: 76% vs. 76%, p\u2009=\u20090.837; subjective: 78% vs. 83%, p\u2009=\u20090.212). There were no significant differences in adverse events, except SISs had a shorter surgery time (16.4\u2009±\u20099.3 vs. 27.3\u2009±\u200912.4 min, p\u2009=\u20090.020) and lower postoperative visual analog scale pain score (1.3\u2009±\u20091.1 vs. 3.9\u2009±\u20091.4, p\u2009<\u20090.001). SISs and TOSs had similar surgical results in women with stress incontinence and ISD after at least 1 year of follow-up. However, SISs had a shorter operation time and lower postoperative pain than TOSs.