European Journal of Applied Physiology | 2019
Oxygen uptake plateau: calculation artifact or physiological reality?
Abstract
Purpose To test whether the oxygen uptake ( $$\\dot{V}O_{{2}}$$ V ˙ O 2 ) plateau at $$\\dot{V}O_{{{\\text{2max}}}}$$ V ˙ O 2max is simply a calculation artifact caused by the variability of $$\\dot{V}O_{{2}}$$ V ˙ O 2 or a clearly identifiable physiological event. Methods Forty-six male participants performed an incremental ramp and a $$\\dot{V}O_{{{\\text{2max}}}}$$ V ˙ O 2max verification test. Variability of the difference between adjacent sampling intervals (difference) and of the slope of the $$\\dot{V}O_{{2}}$$ V ˙ O 2 –workload relationship (slope) in the submaximal intensity domain were calculated. Workload defined sampling intervals used for the calculation of the difference and slope were systematically increased from 20 to 100\xa0W until the expected risk of false plateau diagnoses based on the Gaussian distribution function was lower than 5%. Overall, more than 1500 differences and slopes were analyzed. Subsequently, frequencies of plateau diagnoses in the submaximal and maximal intensity domains were compared. Results Variability of the difference and slope decreased with increasing sampling interval ( p \u2009<\u20090.001). At a sampling interval of 50\xa0W, the predefined acceptable risk of false plateau diagnoses (≤ 5%) was achieved. At this sampling interval, the actual frequency (1.4%) of false-positive plateau diagnoses did not differ from the expected frequency in the submaximal intensity domain (1.6%; p \u2009=\u20090.491). In contrast, the actual frequency at maximal intensity (35.7%) was significantly higher compared to the submaximal intensity domain ( p \u2009<\u20090.001) and even higher than the expected frequency of false-positive diagnoses ( p \u2009<\u20090.001). Conclusion The $$\\dot{V}O_{{2}}$$ V ˙ O 2 plateau at $$\\dot{V}O_{{{\\text{2max}}}}$$ V ˙ O 2max represents a physiological event and no calculation artifact caused by $$\\dot{V}O_{{2}}$$ V ˙ O 2 variability. However, detecting a $$\\dot{V}O_{{2}}$$ V ˙ O 2 plateau with sufficient certainty requires large sampling intervals.