CRISPR-mediated gene editing to rescue haploinsufficient obesity syndrome

Abstract

Zhifeng Wang, Liu Yang, Shen Qu, Chao Zhang 1 Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China 2 Research & Development Department, Sinoneural Cell and Gene Engineering Holdings Co., Ltd., Shanghai, China 3 Department of Endocrinology and Metabolism, National Metabolic Management Center, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai 200092, China & Correspondence: [email protected] (S. Qu), [email protected] (C. Zhang)