“Recurrence or Retro-conversion? A Diagnostic Dilemma”: Case Report and Review of Literature on Growing Teratoma Syndrome (GTS)

Abstract

Growing teratoma syndrome (GTS) is a rare entity which consists of benign enlarging teratoma after chemotherapy. The understanding of such phenomenon is important as misinterpretation can be taken as disease progression and lead to mismanagement. The exact etiopathogenesis is still questionable, but it has a well-defined disease scenario. The surgical treatment is the only curative modality as it is a chemotherapy- and radiotherapy-resistant disease. We present a case of ovarian immature teratoma who after chemotherapy presented with increased tumor size. Histopathology of the resected specimen confirmed the diagnosis of mature teratoma leading to recognition of GTS.