Total synthetic approaches for lucidone: a promising natural lead candidate against dengue infection

Abstract

Abstract Lucidone, isolated from the dried fruits of Lindera lucida and Lindera erythrocarpa Makino (family: Lauraceae), belongs to the naturally occurring cyclopentenediones and has recently been demonstrated to exhibit therapeutic potential against the dengue virus (DENV). Drug development against DENV is urgently needed in the current global scenario and this chapter focuses on the total synthetic approaches of this important natural molecule to boost the ongoing research.