Intracoronary thrombus by Optical Coherence Tomography (OCT): Characterization, quantification and prognostic impact in patients with non-ST-elevation acute coronary syndrome. A DOCTORS substudy

Abstract

Background We evaluated the impact of thrombus burden as measured by Optical Coherence Tomography on the occurrence of periprocedural myocardial infarction (type IVa MI) in pts undergoing percutaneous coronary intervention (PCI) in non ST elevation acute coronary syndrome (NSTE-ACS). Methods Prospective multicenter study including pts treated for NSTE-ACS ( Results Hundred and twenty pts aged 60.8\xa0±\xa011 years were included. Thrombus was more frequently present on OCT [83 (69%)] than on angiography [54 (45%), P\xa0 Conclusion OCT allows better visualization of thrombus than angiography in NSTE-ACS. In pts receiving antithrombotic therapy, neither the presence nor the volume of thrombus impacts the occurrence of a periprocedural myocardial infarction. Thrombus burden does not influence the functional outcome of angioplasty as measured by FFR.