COVID-19 in young patients: Less cardiovascular risk factors but more specific cardiovascular complications

Abstract

Background Main features of COVID-19 patients have been reported in the literature. While young patients under 45 years old (y/o) account for a non-negligible part of hospitalized patients, data on this population remain sparse. Purpose To describe the characteristics and outcomes of hospitalized COVID-19 young patients ( Methods The Critical COVID France (CCF) study was an observational multicenter study including patients hospitalized for COVID-19. Primary composite outcome included transfer to ICU or in-hospital death. Secondary outcomes were cardiovascular complications diagnosed by the referring medical team according to available clinical, biological and radiological findings. Results Among 2,878 patients hospitalized for COVID-19 in 24 centers, 321 (11.2%) patients were under the age of 45 y/o. They had a higher body mass index (BMI) (28.9\xa0±\xa06.6 vs 27.7\xa0±\xa06.0, P\xa0=\xa00.004) but less other cardiovascular risk factors including hypertension (29 (9.2%) vs. 1422 (56.1%), P\xa0 \xa045 y/o (P\xa0 \xa045 y/o (183 (7.2%) vs. 3 (0.9%), P\xa0 Fig. 1 ). Conclusion In this nationwide multicenter observational study of hospitalized COVID-19 patients, patients under the age of 45 y/o had less cardiovascular risk factors but more specific related COVID-19 cardiovascular complications such as pericarditis and myocarditis.