Daylight-driven rechargeable, antibacterial, filtrating micro/nanofibrous composite membranes with bead-on-string structure for medical protection

Abstract

Abstract Drug-resistant pathogens render tremendous pressure and challenges on the development of biomedical materials with highly efficient barrier and long-lasting antibacterial efficacy. Herein, this study combined metal–organic framework (zeolite imidazolate framework 8 [ZIF-8]) and melt blowing–electrospinning method to construct the bead-on-string structure of PPCL@PDA/TAEG/PCL/ZIF8 hierarchical micro/nanofibrous composite membranes with rechargeable, antibacterial, and high-efficiency filtration properties. The incorporation of bead-on-string structure provides the PPCL@PDA/TAEG/PCL/ZIF8–9 composite membranes with above 99.9% filtration efficiency against ultrafine particles larger than 500 nm in diameter. Moreover, the composite membrane quickly releases reactive oxygen species under daylight conditions. The release amount after charging for 1 hour is 13009.41 μg/g for •OH and 405.72 μg/g for H2O2. The composite membranes retain 89.9% and 65.1% of the original charging capacities of •OH and H2O2, respectively, after seven cycles. These membranes also show greater antibacterial activity, and the sterilizing rates against S. aureus and E. coli reach 99% and 95%, respectively, in daytime and nighttime. These daylight-driven rechargeable micro/nanofibrous membranes can be used in the development of reusable medical protective materials with highly efficient filtration and daylight-driven rechargeable antibacterial efficacy.