Journal of Dental Sciences | 2021
Granular cell tumor: Case report
Abstract
tps://doi.org/10.1016/j.jds.2021.02. 91-7902/a 2021 Association for Denta e CC BY-NC-ND license (http://creati Granular cell tumor is a rare benign soft tissue tumor of Schwann cell origin. It shows a predilection for the oral cavity, especially the dorsal surface of the tongue. Here, we presented a granular cell tumor at the right lateral border of the tongue of a 41-year-old male patient. This 41-year-old male patient came to our oral and maxillofacial surgery clinic for evaluation of a mass at the right lateral border of the tongue for several weeks. Intraoral examination did not reveal any elevated tumor at the right lateral border of the tongue, but a firm mass measuring approximately 1.0 cm in greatest dimension was palpable at the submucosal area of the right lateral border of the tongue. The tumor was painless. Because the origin of the tumor was uncertain and the tumor was relatively small, the tentative treatment plan was total excision of the tumor. After discussing with the patient and obtaining the signed informed consent, the tumor was totally excised under local anesthesia. The removed soft tissue tumor specimen was sent for histopathological examination. Microscopically, the tumor was covered by slightly hyperplastic parakeratinized stratified squamous epithelium (Fig. 1A). The mediumand high-power views showed sheets or nests of large, polygonal tumor cells with abundant slightly basophilic and granular cytoplasm and vesicular nuclei infiltrating among skeletal muscle fibers (Fig. 1B and C). The cell borders were indistinct and some cells seemed to fuse together to show a syncytial