Effect of Sn addition on the mechanical properties and bio-corrosion behavior of cytocompatible Mg–4Zn based alloys

Abstract

Abstract The mechanical properties and bio-corrosion behaviors of as-extruded Mg–4Zn alloys after Sn addition were investigated, systematically. A small amount of Sn addition to Mg–4Zn alloy slightly improved the mechanical properties for solid solution strengthening, and significantly controlled the bio-corrosion rates. Sn participating in the outer layer film formation as SnO/SnO2 resisted the bio-corrosion proceeding. Especially, Mg–4Zn–1.5Sn alloy, with a weight loss rate of 0.45\u202fmm/y and hydrogen evolution rate of 0.099\u202fmL/cm2/day, showed cytotoxicity grade of 0 to MC3T3-E1 cells. The perfect alliance of cytocompatibility, suitable mechanical properties and low bio-corrosion rate demonstrates that this Mg–4Zn–1.5Sn alloy is a promising biodegradable magnesium alloy for orthopedic implants.