Effects of dietary curcumin and acetylsalicylic acid supplements on performance, muscle amino acid and fatty acid profiles, antioxidant biomarkers and blood chemistry of heat-stressed broiler chickens.

Abstract

The objective was to investigate the effects of dietary curcumin and acetylsalicylic acid (ASA) on the performance and physiological responses of broiler chickens under chronic thermal stress. One hundred and sixty day-old male chicks (Ross 308) were divided equally into 4 groups (each contained 4 replicates). On the day 22 of age and thereafter, the first group (TN) was raised in a thermoneutral condition (23\u202f±\u202f1\u202f°C), while the second group (HS) was subjected to 8\u202fh of thermal stress (34\u202f°C) and both groups fed the basal diet with no supplements. The third (CR) and fourth (AS) groups were subjected to the same thermal stress conditions and fed curcumin-supplemented diet (100\u202fmg curcumin kg-1 diet) and ASA-supplemented diet (1\u202fg ASA kg-1 diet), respectively. Dietary treatment had a significant effect on ADFI (P\u202f=\u202f0.041), average daily gain (P\u202f=\u202f0.013) and final body weight (P\u202f=\u202f0.001). The curcumin-supplemented had higher values for these measures compared with other experimental groups (P\u202f<\u202f0.05). Also, the dietary curcumin supplement significantly increased the carcass yield as compared to the HS group (P\u202f<\u202f0.05). Compared with the HS group, the dietary curcumin and ASA supplements decreased the concentration of malondialdehyde in the breast muscles (P\u202f=\u202f0.014). Both dietary supplements exhibited a marked ability to restore the serum TAC, Na and K in heat-stressed broiler chickens. The current study reported a remarkable ability of curcumin supplement to restore the concentrations of polyunsaturated fatty acids (PUFA) in the breast muscles of heat-stressed broilers, including α-linolinec acid and Docosahexaenoic acid (P\u202f=\u202f0.009 and 0.001, respectively). It could be concluded that supplemental dietary curcumin or ASA enhanced growth performance and antioxidant biomarkers of heat-stressed broilers. Moreover, curcumin might be an effective dietary supplement to alleviate the adverse effect of chronic thermal stress on carcass yield and meat quality.