Investigating wound healing potential of Typha angustata L. inflorescence in albino Wistar rats

Abstract

Abstract Background Typha angustata L. is a common aquatic weed. Although the folkloric use of Typha in wound healing has been reported, scientific evidences are still lacking. Purpose The present study aimed to explore the wound healing potentials of T. angustata L. Method The ointment was prepared from the aqueous extract of Typha inflorescence and applied on the induced wounds (viz., Excision, Incision and Burn) in albino Wistar rats. Continuous monitoring of percentage of wound contraction, epithelization duration, content of hydroxyproline and protein (from the excised wound tissues collected on 14th and 28th day of treatment) were used as parameters to know wound healing effects. In addition, catalase activity (antioxidant marker) and histopathological studies were also carried out. Results Topical application of the test ointment showed significant (p Conclusion The results of the present study suggest the potentials of Typha plant in formulating wound healing agents.