Cinnacetals A and B: Two highly oxidated and modified isoryanodane diterpenoids from Cinnamomum cassia

Abstract

Abstract Cinnacetals A and B (1 and 2), two unprecedented conjugates of highly oxidated and modified isoryanodane diterpenoids featuring cinnamaldehyde derived moieties of 1,3-dioxane and 1,3-dioxolane, respectively, were isolated from the twigs and leaves of Cinnamomum cassia. Their structures were determined by spectroscopic methods, single-crystal X-ray diffraction analysis and the TDDFT-based electronic circular dichroism (ECD) calculation.