Tetrahedron | 2019
DDQ-promoted direct C–H amination of ethers with N-alkoxyamides under visible-light irradiation and metal-free conditions
Abstract
Abstract A C(sp3)–N bond forming reaction between N-alkoxyamides and simple ethers has been developed. In the presence of commercially available 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ), a variety of N-methoxyamides and ethers undergo this transformation smoothly to deliver the corresponding products in good yields under visible-light irradiation and metal-free conditions at room temperature.