Sex and Gender Differences in Alzheimer s Disease | 2021
Sex and gender considerations in clinical trials for Alzheimer’s disease: Current state and recommendations
Abstract
Abstract This chapter describes the current situation regarding sex and gender considerations in clinical trials from preclinical research in animal models to large efficacy trials. Despite women comprise two-thirds of the AD population, for several reasons discussed in this chapter such as eligibility criteria or sociocultural factors, women are underrepresented in clinical trials. We provide a set of recommendations that should help revert this situation.