PROgnostic value at one year of the frailty level evaluated by the SEGA score for octogenarians presenting an acute COronary syndrome: PROSECO study

Abstract

Background SEGA score has shown interesting performance in screening for frailty both at home and in emergency services. However, its predictive abilities in elderly patients presenting an acute coronary syndrome have not yet been evaluated. Purpose To study the prognostic value at one year of the level of frailty assessed by the SEGA score in a population of patients aged 80 years old or more hospitalised for acute coronary syndrome. Methods All consecutive patients aged 80 or older hospitalised for an acute coronary syndrome type 1 between November 2016 and October 2017 were included. They all had a standardised geriatric assessment including an estimation of the level of frailty by the SEGA score. The primary outcome was the delay to death from any cause. Results Sixty-four patients were included. “Very frail” patients (SEGA greater than 11) had a non-significant tendency to an increased risk of death (HR to 1.9, 95% CI 0.74 to 4.8, P\xa0=\xa00.19). Patients aged 85 years or more and those with a body mass index of 21\xa0kg/m2 or less had a higher risk of death (P\xa0=\xa00.007 and P\xa0=\xa00.018 respectively). In multivariate analysis, only arterial hypertension and age 85 years or more were independently associated with the risk of death (P\xa0 Conclusions Frailty defined by the SEGA score (physical, psychic and social frailty) was not related to the risk of death in our population.