Horizons and Group Motivational Enhancement Therapy: HIV Prevention for Alcohol-Using Young Black Women, a Randomized Experiment.

Abstract

INTRODUCTION\nBlack women are at disproportionately greater risk for HIV and sexually transmitted infections than women of other ethnic/racial backgrounds. Alcohol use may further elevate the risk of HIV/sexually transmitted infection acquisition and transmission.\n\n\nSTUDY DESIGN\nA random-assignment parallel-group comparative treatment efficacy trial was conducted with random assignment to 1 of 3 conditions.z SETTING/PARTICIPANTS: The sample comprised 560 Black or African American women aged 18-24 years who reported recent unprotected vaginal or anal sex and recent alcohol use. Participants were recruited from community settings in Atlanta, Georgia, from January 2012 to February 2014.\n\n\nINTERVENTION\nA Group Motivational Enhancement Therapy module was designed to complement a Centers for Disease Control and Prevention-designated evidenced-based intervention (Horizons) to reduce sexual risk behaviors, alcohol use, and sexually transmitted infections, with 3 comparison groups: (1) Horizons\u202f+\u202fGroup Motivational Enhancement Therapy intervention, (2) Horizons\u202f+\u202fGeneral Health Promotion intervention, and (3) enhanced standard of care.\n\n\nMAIN OUTCOME MEASURES\nOutcome measures included safe sex (abstinence or 100% condom use); condom nonuse; proportion of condom use during sexual episodes; incident chlamydia, gonorrhea, and trichomonas infections; and problematic alcohol use measured by Alcohol Use Disorders Identification Test score. Treatment effects were estimated using an intention-to-treat protocol‒generalized estimating equations with logistic regression for binomial outcomes and Poisson regression for count outcomes. Analyses were conducted between October 2018 and October 2019.\n\n\nRESULTS\nParticipants assigned to Horizons\u202f+\u202fGroup Motivational Enhancement Therapy had greater odds of safe sex (AOR=1.45, 95% CI=1.04, 2.02, p=0.03), greater proportion of condom use (AOR=1.68, 95% CI=1.18, 2.41, p=0.004), and lower odds of condom nonuse (AOR=0.57, 95% CI=0.38, 0.83, p=0.004). Both interventions had lower odds of problematic alcohol use (Horizons: AOR=0.57, 95% CI=0.39, 0.85, p=0.006; Horizons\u202f+\u202fGroup Motivational Enhancement Therapy: AOR=0.61, 95% CI=0.41, 0.90, p=0.01).\n\n\nCONCLUSIONS\nComplementing an evidence-based HIV prevention intervention with Group Motivational Enhancement Therapy may increase safer sexual behaviors and concomitantly reduce alcohol use among young Black women who consume alcohol.\n\n\nTRIAL REGISTRATION\nThis study is registered at www.clinicaltrials.gov NCT01553682.