Cardiovascular revascularization medicine : including molecular interventions | 2019
Impact of different final optimization techniques on long-term clinical outcomes of left main cross-over stenting.
Abstract
BACKGROUND\nThe optimal final optimization technique to be used in patients after Cross Over Left main stenting remainsdebatable.\n\n\nAIM\nWe evaluate the impact of the post-optimization technique (POT), kissing balloon (KB) and the POT-side-POT techniques on both cardiovascular mortality and event-free survival in patients receiving left main (LM) cross-over stenting for an isolated/distal bifurcation LM disease.\n\n\nMETHODS\nClinical and instrumental records of 128 consecutive patients (102 males, mean age 73.39\u202f±\u202f9.54\u202fyears old) with isolated distal/bifurcation LM disease and bypass surgery contraindications or refusal enrolled to receive LM cross-over stenting between the 1st January 2012 and the 1st January 2017 at two institutions: the Rovigo General Hospital (Rovigo, Italy) and the Alexandrovka Hospital University School of Medicine (Sofia, Bulgaria). Patients has been divided into three groups (POT, KB and POT-side-POT) according the optimal final optimization technique used while the 5-year cardiovascular mortality has been evaluated using the log-rank (Mantel-Cox) analysis.\n\n\nRESULTS\nBaseline angiographic characteristics of the LM disease were mostly equivalent among the three groups. Over a global follow-up of 61.03\u202f±\u202f0.92\u202fmonths, the rates of target vessel revascularization, acute myocardial infarction, and stent thrombosis, were not different among groups. Patients treated with POT had a slightly better long-term survival.\n\n\nCONCLUSIONS\nNone of these optimization techniques appeared to have clearly better long-term outcomes after LM Cross-over stenting in our retrospective study. POT resulted in a slightly better survival compared to Pot-sid-POT and KB.