Chem Catalysis | 2021
7-Membered rings made easy
Abstract
The stereoselective synthesis of functionalized, saturated N-heterocycles is a key challenge in modern synthesis and introduces avenues toward three-dimensional building blocks with vast potential in drug discovery. In this issue of Chem Catalysis, Blanc and co-workers report a Au(I)-catalyzed stereoselective cascade reaction that paves the way toward highly functionalized azepines.