Exercise associated or not to the intake of Eurycoma longifolia improves strength and cardiorespiratory fitness in men with androgen deficiency.

Abstract

This study aims to analyze the effects of a concurrent training (CT) associated with Eurycoma longifolia (EL) supplementation on the muscle strength, cardiorespiratory fitness, and symptomatology score of men with the androgen deficiency of aging male (ADAM). Forty-five subjects (47.6\xa0±\xa05.2 years) were included in the study. The randomized, double-blinded, placebo controlled clinical trial lasted for 6 months. Participants were randomized into four groups, control (C; n\xa0=\xa012); EL (n\xa0=\xa011); CT (n\xa0=\xa011); and CT\xa0+\xa0EL (n\xa0=\xa011). Along this period, the isokinetic peak torque of the knee extensors increased in the CT (14%) and CT\xa0+\xa0EL (17%) groups (p\xa0=\xa00.040; p\xa0=\xa00.006, respectively), while the isokinetic peak torque of knee flexion increased in the CT\xa0+\xa0EL group only (p\xa0<\xa00.05). For all participants, testosterone levels were correlated with isokinetic peak torque of knee extension (r\xa0=\xa00.517, p\xa0=\xa00.001) and flexion (r\xa0=\xa00.362, p\xa0=\xa00.028). Subjects of the CT (27.3%) and CT\xa0+\xa0EL (36.1%) groups decreased the symptomatology of ADAM (p\xa0=\xa00.005). This study demonstrated the benefits of CT and EL consumption as a non-pharmacological treatment for ADAM.