Nonmuscle myosin-2 isoforms

Abstract

A hallmark of eukaryotes is the ability to generate microscale movements from the molecular to the tissue-length scales. Members of the myosin and actin protein families form the actomyosin cytoskeleton and are responsible for these movements. The cytoskeleton is a diffuse and dynamic network made up of different actin structures including arcs, bundles and single filaments, which are often associated with actin regulatory proteins. As such, it spans the entire cell and provides it with structural support.