Does informant-based reporting of cognitive symptoms predict amyloid positivity on positron emission tomography?

Abstract

Researchers are searching for clinical instruments to predict amyloid positivity for disease classification. Informant‐based reports could detect disease status. This study compares subjective memory complaints captured by informant‐based reports between positron emission tomography (PET)–positive and PET‐negative patients and hypothesizes that amyloid PET positivity associates with increased informant‐based cognitive complaints.