An ERK Phosphoproteome Expands Chemotactic Signaling in Dictyostelium.

Abstract

In this issue of Developmental Cell, Nichols et\xa0al. (2019) establish the MAP kinase ErkB as a critical component for chemotaxis signaling in Dictyostelium. Using phosphoproteomics, they identify a chemoattractant-dependent ErkB targeted core set of signal transduction proteins, which collectively suggest an added mechanistic pathway for chemotactic regulation.