Temporal trend of newly diagnosed type 1 diabetes children and adolescents identified over a 35-year period in a Brazilian institution.

Abstract

AIMS\nTo evaluate the temporal trend of newly diagnosed Type 1 Diabetes cases over a 35-year period in a reference Pediatric Endocrinology service in the city of Belo Horizonte, Brazil.\n\n\nMETHODS\nSubjects were all children and adolescents diagnosed with Type 1 Diabetes in the Federal University of Minas Gerais Hospital. Information collected included: gender, age and date of Type 1 diabetes diagnosis. Temporal trends were analyzed between 1980 and 2014 and divided in 5-year intervals.\n\n\nRESULTS\nDuring this period 642 children and adolescents were diagnosed with Type 1 diabetes. From 1980 to 1994 there was an increase in the proportion of children diagnosed between 0 and 4\u202fyears old, followed by progressive decrease in the subsequent decades (47% in 1990-1994 to 20% in 2010-2014; p\u202f=\u202f0.01). There was an increase in the proportion of children diagnosed between 10 and 18\u202fyears old (13% in 1990-1994 to 54% in 2010-2014; p\u202f=\u202f0.01). There was no statistical difference in the proportion of children diagnosed between 5 and 9\u202fyears old through the studied time.\n\n\nCONCLUSIONS\nIn the studied population Type 1 Diabetes in infants and toddlers seems to be decreasing throughout the years while in the age group older than 10\u202fyears, it seems to be increasing.